The National Institute of Dental and Craniofacial Research (NIDCR) intends to publish a Notice of Funding Opportunity (NOFO) to promote practice-based research through a Dental Primary Care Practice-Based Research Network (PBRN). This NOFO will invite applications for an Administrative and Resource Center (ARC), to support the infrastructure for the planning and implementation of multiple observational studies and clinical trials, together with a Coordinating Center, described in a separate companion NOFO. Supported studies will focus on integrating oral health care into medical care (whole-person health). The ARC will be responsible for recruiting and retaining practitioners for network membership and study participation, managing a single IRB, ensuring that practitioners and office/clinic staff receive research and study-specific training, and coordinating study deployment across multiple U.S. geographic regions (i.e., Nodes). Applications are not being solicited at this time. Notice is being provided to allow potential applicants time to develop meaningful collaborations and responsive projects. Investigators with expertise in study coordination and conducting clinical research in practice-based research settings are encouraged to apply. NIDCR is authorized to forecast this opportunity under the Public Health Service Act (42 U.S.C §§ 241 and 284) and federal regulations (42 CFR Part 52 and 2 CFR Part 200).

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