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Seed Instrumentation Support (SIS) Program (S10 Clinical Trial Not Allowed)

Agency: National Institutes of Health

Assistance Listings: 93.351 -- Research Infrastructure Programs

Last Updated: November 19, 2025

Description

This Notice of Funding Opportunity (NOFO) aims to build new research capacity by supporting the purchase of a single commercially available biomedical research instrument currently unavailable in the institution. Instruments funded through this program must be shared among the users to create new research opportunities, enable reproducible data generation, encourage collaborative research and training, and strengthen long-term research capabilities. The minimum award is $50,000. While there is no limit on the total cost of the instrument, the maximum award is $400,000. 

Eligibility

Eligible applicants

Nonprofit

  • Nonprofits non-higher education with 501(c)(3)
  • Nonprofits non-higher education without 501(c)(3)

Education

  • Public and state institutions of higher education
  • Private institutions of higher education

Additional information

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Grantor contact information

Description

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Email

xiang-ning.li@nih.gov

xiang-ning.li@nih.gov

Documents

No documents are currently available.

Link to additional information

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Forecasted

Estimated Post Date:

February 28, 2026

Estimated Application Due Date:

July 1, 2026

Estimated Due Date Description:

Not available

Estimated Award Date:

May 1, 2027

Estimated Project Start Date:

May 1, 2027

Fiscal Year:

2027

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$5,000,000

Program Funding

15

Expected awards

$50,000

Award Minimum

$400,000

Award Maximum

Funding opportunity number:

PAR-26-074

Cost sharing or matching requirement:

No

Funding instrument type:

Grant

Opportunity Category:

Discretionary

Opportunity Category Explanation:

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Category of Funding Activity:

Health

Category Explanation:

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History

Version:

1

Forecast posted date:

November 19, 2025

Archive date:

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