Identify and Characterize Potential Environmental Risk Factors for Amyotrophic Lateral Sclerosis (ALS) and Evaluate Their Impact on ALS Disease Incidence and Progression

The Agency for Toxic Substances and Disease Registry (ATSDR) is soliciting investigator-initiated research that will identify and characterize environmental toxicants in human biological samples that may be potential environmental risk factors for Amyotrophic Lateral Sclerosis (ALS). Applications are also sought that will evaluate the impact of environmental toxicants on the development and progression of ALS, including gene-environment interactions. Information gleaned from this investigator-initiated research will provide a greater understanding of the possible link between exposures to environmental toxicants and the etiology of ALS.

The following types of Higher Education Institutions are always encouraged to apply for CDC support as Public or Private Institutions of Higher Education: Hispanic-serving InstitutionsHistorically Black Colleges and Universities (HBCUs) Tribally Controlled Colleges and Universities (TCCUs)Alaska Native and Native Hawaiian Serving InstitutionsNonprofits Other Than Institutions of Higher Education:Nonprofits (Other than Institutions of Higher Education)Other:Native American tribal organizations (other than Federally recognized tribal governments)Faith-based or Community-based OrganizationsRegional OrganizationsBona Fide Agents: a Bona Fide Agent is an agency/organization identified by the state as eligible to submit an application under the state eligibility in lieu of a state application. If applying as a bona fide agent of a state or local government, a legal, binding agreement from the state or local government as documentation of the status is required. Attach with "Other Attachment Forms" when submitting viawww.grants.gov.Federally Funded Research and Development Centers (FFRDCs): FFRDCs are operated, managed, and/or administered by a university or consortium of universities, other not-for-profit or nonprofit organization, or an industrial firm, as an autonomous organization or as an identifiable separate operating unit of a parent organization. A FFRDC meets some special long-term research or development need which cannot be met as effectively by an agency's existing in-house or contractor resources. FFRDC's enable agencies to use private sector resources to accomplish tasks that are integral to the mission and operation of the sponsoring agency.

CDC Technical Information Management Section (TIMS) Telephone 770-488-2700 Email: ogstims@cdc.gov