Opportunity Listing - Revision Applications for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (R01 Clinical Trial Optional)

Revision Applications for Incorporation of Novel NCI-Supported Technology to Accelerate Cancer Research (R01 Clinical Trial Optional)

Agency: National Institutes of Health

Assistance Listings: 93.394 -- Cancer Detection and Diagnosis Research

Last Updated: December 9, 2025

Description

The purpose of this Notice of Funding Opportunity (NOFO) is to encourage revision applications (formerly called "competing revisions") from currently funded NCI R01 research projects. The applicants should propose to expand upon the original research question(s) or otherwise accelerate progress for the parent study by incorporating a new technical approach or device developed through support from the NCI Innovative Molecular Analysis Technologies (IMAT) program. Awards from this NOFO are meant to incentivize independent validation and accelerate the adoption of these emerging technologies by appropriate research communities.As a component of the NCI IMAT program, this NOFO aims to promote interdisciplinary collaboration in the development of innovative tools and methods that enable cancer research and accelerate scientific discovery.

Eligibility

Eligible applicants

Government

Public and Indian housing authorities
Special district governments
Federally recognized Native American tribal governments
State governments
City or township governments
County governments

Education

Independent school districts
Private institutions of higher education
Public and state institutions of higher education

Nonprofit

Nonprofits non-higher education without 501(c)(3)
Other Native American tribal organizations
Nonprofits non-higher education with 501(c)(3)

Business

For-profit organizations other than small businesses
Small businesses

Miscellaneous

Other

Additional information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Documents

File name	Description	Last updated
RFA-CA-25-005-Full-Announcement.html	RFA-CA-25-005 Full Announcement Text	Dec 31, 2024 05:27 PM UTC

Link to additional information

https://grants.nih.gov/grants/guide/rfa-files/RFA-CA-25-005.html

Closed: December 9, 2025

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$150,000

Program Funding

Expected awards

$--

Award Minimum

$150,000

Award Maximum

Funding opportunity number:

RFA-CA-25-005

Cost sharing or matching requirement:

Funding instrument type:

Grant

Opportunity Category:

Discretionary

Opportunity Category Explanation:

Category of Funding Activity:

Education

Health

Category Explanation:

History

Version:

Posted date:

December 31, 2024

Archive date:

February 7, 2026