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Exploratory/Developmental Grants Related to the World Trade Center Health Program (R21)

Agency: Centers for Disease Control and Prevention - ERA

Assistance Listings: 93.262 -- Occupational Safety and Health Program

Last Updated: October 15, 2025

Description

The World Trade Center (WTC) Health Program supports exploratory and developmental research projects (R21) that address issues related to diagnostic or treatment uncertainty with respect to individuals receiving monitoring and/or treatment under subtitle C of the James Zadroga 9/11 Health and Compensation Act of 2010 as amended. This WTC Health Program R21 Notice of Funding Opportunity (NOFO) is intended to encourage exploratory/developmental research by providing support for the early and conceptual stages of project development which assess the feasibility of new areas of investigation with the potential to enhance treatment effectiveness and diagnostic practices. These studies may lead to breakthroughs in a particular area, or to the development of new interventions, techniques, agents, methodologies, models, or approaches with major clinical impacts. These studies are expected to break new ground or extend prior discoveries toward new directions or uses. Applicants are expected to propose research for which there is likely to be minimal or no preliminary data.

Eligibility

Eligible applicants

Government

  • Federally recognized Native American tribal governments
  • County governments
  • City or township governments
  • State governments
  • Public and Indian housing authorities
  • Special district governments

Education

  • Private institutions of higher education
  • Independent school districts
  • Public and state institutions of higher education

Miscellaneous

  • Unrestricted

Business

  • Small businesses
  • For-profit organizations other than small businesses

Nonprofit

  • Nonprofits non-higher education with 501(c)(3)
  • Other Native American tribal organizations
  • Nonprofits non-higher education without 501(c)(3)

Additional information

Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the HHS Grants Policy Statement, are not allowed.

Grantor contact information

Description

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Email

fzt4@cdc.gov

fzt4@cdc.gov

Documents

No documents are currently available.

Link to additional information

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Forecasted

Estimated Post Date:

December 5, 2025

Estimated Application Due Date:

February 12, 2026

Estimated Due Date Description:

Not available

Estimated Award Date:

June 1, 2026

Estimated Project Start Date:

July 1, 2026

Fiscal Year:

2026

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$30,000,000

Program Funding

60

Expected awards

$--

Award Minimum

$365,000

Award Maximum

Funding opportunity number:

RFA-OH-26-015

Cost sharing or matching requirement:

No

Funding instrument type:

Grant

Opportunity Category:

Discretionary

Opportunity Category Explanation:

--

Category of Funding Activity:

Health

Category Explanation:

--

History

Version:

1

Forecast posted date:

October 15, 2025

Archive date:

December 1, 2029

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