Eradication of Invasive Quagga and Zebra Mussels Using Engineered Disseminated Neoplasia
Agency: Bureau of Reclamation
Assistance Listings
- 15.560 -- SECURE Water Act – Research Agreements
Archived opportunityLast Updated: May 13, 2026
View version history on Grants.gov
Description
Under this Agreement, Biomilab, LLC. shall work to engineer normal quagga and zebra mussel hemocytes into “induced” DN cells (iDNCs) that can be used to transmit and foster lethal cancer into populations of these invasive species in open waters. Major tasks for the project include, but are not limited to:
• Establish a facility for the maintenance of live zebra and quagga mussels
• Determine methods and conditions for extended culture of explanted and dissociated mussel cells, and establish methods for their genetic modification
...
• Determine methods for the transplantation/engraftment and survival of cultured cells to live mussels and complete characterization of target genes and gene products for use in genomic modification
• Convert dreissenid mussel hemocytes to genetically-modified hemic disseminated neoplasia cells (iDNCs) and establishment of methods for long-term culture, expansion, and cryopreservation of iDNCs
• Introduction of iDNCs to live quagga/zebra mussels and control mussels, and analysis of engraftment, dissemination, and toxicity
Eligibility
Eligible applicants
Miscellaneous
- Other
Additional information
Biomilab, Inc.
Grantor contact information
Description
Irene M Hoiby
Supervisory Grants Management Specialist
Phone 303-445-2025
Grants Officer
Documents
| File name | Description | Last updated |
|---|---|---|
| NOI-BOR-19-N020-Post.pdf | Notice of Intent to Award | Jun 18, 2019 08:31 PM UTC |
Link to additional information
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Archived: June 28, 2019
Award
$--
Program Funding
1
Expected awards
$1
Award Minimum
$1,500,000
Award Maximum
Funding opportunity number:
BOR-DO-19-N020
Cost sharing or matching requirement:
No
Funding instrument type:
Cooperative agreement
Opportunity Category:
Discretionary
Opportunity Category Explanation:
--
Category of Funding Activity:
Science technology and other research and development
Category Explanation:
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History
Version:
1
Posted date:
June 18, 2019
Archive date:
June 28, 2019
