Opportunity Listing - Research on Current Topics in Alzheimer's Disease and Its Related Dementias (R21 Clinical Trial Optional)

Research on Current Topics in Alzheimer's Disease and Its Related Dementias (R21 Clinical Trial Optional)

Agency: National Institutes of Health

Assistance Listings: 93.121 -- Oral Diseases and Disorders Research

93.866 -- Aging Research

Last Updated: November 20, 2025

Description

The purpose of this Notice of Funding Opportunity (NOFO) is to invite applications proposing new tests, animal models, techniques, etc. to advance research on Alzheimer's disease (AD) and its related dementias (ADRD) that need additional preliminary data with broader dissemination to establish them for more general use in this research field. The priority topics will be announced through a series of Notices published subsequent to this NOFO.

Eligibility

Eligible applicants

Education

Public and state institutions of higher education
Independent school districts
Private institutions of higher education

Nonprofit

Other Native American tribal organizations
Nonprofits non-higher education with 501(c)(3)
Nonprofits non-higher education without 501(c)(3)

Government

Public and Indian housing authorities
Federally recognized Native American tribal governments
State governments
County governments
City or township governments
Special district governments

Business

Small businesses
For-profit organizations other than small businesses

Miscellaneous

Other

Additional information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Documents

File name	Description	Last updated
PAR-25-331-Full-Announcement.html	PAR-25-331 Full Announcement Text	Dec 30, 2024 03:59 PM UTC

Link to additional information

https://grants.nih.gov/grants/guide/pa-files/PAR-25-331.html

Closed: November 20, 2025

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$--

Program Funding

Expected awards

$--

Award Minimum

$--

Award Maximum

Funding opportunity number:

PAR-25-331

Cost sharing or matching requirement:

Funding instrument type:

Grant

Opportunity Category:

Discretionary

Opportunity Category Explanation:

Category of Funding Activity:

Health

Category Explanation:

History

Version:

Posted date:

December 30, 2024

Archive date:

December 20, 2025