The National Institute of Neurological Disorders and Stroke intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for the Coordinating Center and Testing Sites of the Stroke Preclinical Assessment Network (SPAN), a preclinical network to support translational studies for cerebroprotection in experimental models of acute ischemic stroke.  Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects.  This NOFO will utilize Cooperative Agreements (U01). Investigators with expertise and insights into this area of multi-center translational studies for acute cerebroprotection in experimental models of acute ischemic stroke are encouraged to begin to consider applying for this NOFO. SPAN 3.0 will be a collaborative network for the preclinical testing of stroke treatments comprised of up to 6 peer-reviewed data collection sites that emphasize rigor with built-in replication and a Coordinating Center (CC) that will oversee administration, coordination, and data sharing of the network.

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