Small Business Transition Grant for New Entrepreneurs (R43/R44 Clinical Trial Not Allowed)

Agency: National Institutes of Health

93.273 -- Alcohol Research Programs
93.846 -- Arthritis, Musculoskeletal and Skin Diseases Research
93.879 -- Medical Library Assistance
93.279 -- Drug Abuse and Addiction Research Programs
93.361 -- Nursing Research
93.113 -- Environmental Health
93.867 -- Vision Research
93.121 -- Oral Diseases and Disorders Research
93.859 -- Biomedical Research and Research Training
93.173 -- Research Related to Deafness and Communication Disorders
93.839 -- Blood Diseases and Resources Research
93.840 -- Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders
93.213 -- Research and Training in Complementary and Integrative Health
93.838 -- Lung Diseases Research
93.847 -- Diabetes, Digestive, and Kidney Diseases Extramural Research
93.837 -- Cardiovascular Diseases Research
93.233 -- National Center on Sleep Disorders Research
93.865 -- Child Health and Human Development Extramural Research
93.350 -- National Center for Advancing Translational Sciences
93.262 -- Occupational Safety and Health Program
93.143 -- NIEHS Superfund Hazardous Substances_Basic Research and Education
93.866 -- Aging Research
93.172 -- Human Genome Research

Archived opportunityLast Updated: May 13, 2026

Description

Through this Notice of Funding Opportunity (NOFO), the National Institutes of Health (NIH) aims to facilitate the career development and transition of investigators new to entrepreneurship with an interest in small business by simultaneously supporting their entrepreneurial development and the conduct of research and development under their direction.This NOFO supports small business concerns (SBCs) in employing and developing researchers as entrepreneurial Program Directors/Principal Investigators (PDs/PIs). In addition to augmenting scientific research staff and supporting research and development efforts at SBCs, a major component of this NOFO is entrepreneurial training, mentoring, and career development of the PD/PI. Optimal PDs/PIs for this award are scientists and professionals with strong research, technology development, and/or healthcare delivery skills and experience, but limited entrepreneurial and independent research project leadership experience. PDs/PIs are expected to grow their entrepreneurial skillset while working in a small business to develop promising technologies and products that align with NIH's mission to improve health and save lives.

Eligibility

Eligible applicants

Government

State governments
County governments
City or township governments
Special district governments
Federally recognized Native American tribal governments
Public and Indian housing authorities

Education

Independent school districts
Public and state institutions of higher education
Private institutions of higher education

Nonprofit

Other Native American tribal organizations
Nonprofits non-higher education with 501(c)(3)
Nonprofits non-higher education without 501(c)(3)

Business

For-profit organizations other than small businesses
Small businesses

Miscellaneous

Other

Additional information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, may be allowed.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Documents

File name	Description	Last updated
PAR-24-131-Full-Announcement.html	PAR-24-131 Full Announcement Text	Apr 25, 2024 01:19 PM UTC

Link to additional information

https://grants.nih.gov/grants/guide/pa-files/PAR-24-131.html

Archived: November 18, 2025

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$--

Program Funding

Expected awards

$--

Award Minimum

$--

Award Maximum

Funding opportunity number:

PAR-24-131

Cost sharing or matching requirement:

Funding instrument type:

Grant

Opportunity Category:

Discretionary

Opportunity Category Explanation:

Category of Funding Activity:

Education

Environment

Food and nutrition

Health

Income security and social services

Category Explanation:

History

Version:

Posted date:

April 25, 2024

Archive date:

November 18, 2025