(the funded entities hereafter referred to as “recipients”). The overarching goal for this initiative is to reduce new HIV infections in the United States. To reduce the new HIV infections in the United States, the EHE initiative focuses on four key strategies: •Diagnose all people with HIV as early as possible; •Treat people with HIV rapidly and effectively to reach sustained viral suppression; •Prevent new HIV transmissions by using proven interventions, including pre-exposure prophylaxis (PrEP) and syringe services programs (SSPs); and •Respond quickly to potential HIV outbreaks to get needed prevention and treatment services to people who need them. The role of HRSA HAB and its recipients under HRSA-25-063 is to focus on Treat and Respond. These recipients are encouraged to be creative as they design ways to use EHE initiative funds in conjunction with the current RWHAP Parts A and B systems of care and treatment to end the HIV epidemic in their jurisdictions. The funding directed to the recipients under HRSA-25-063 will allow jurisdictions to implement emerging, evidenced-informed, and/or evidence-based interventions to increase linkage, engagement, and retention in care in addition to funding the additional care and treatment needs of the newly identified and re-engaged individuals. There will be multiple streams of federal resources focused on jurisdictions to help them meet the goals of the EHE initiative. These new and/or expanded resources are in addition to the existing federal HIV resources, creating the need for coordination to ensure the maximum impact of all available resources. HRSA will award one cooperative agreement for each of the following announcement numbers: The TAP funded under HRSA-25-064 is responsible for providing TA to the recipients of HRSA-25-063 on implementation of work plan activities, innovative approaches, and interventions. The SCP funded under HRSA-25-065 is responsible for assisting HRSA-25-063 recipients in coordinating and integrating their initiative plans, funding sources, and programs with the existing HIV care delivery systems. In addition, the SCP will assist in identifying existing and new stakeholders, as well as collate and disseminate best practices, innovative approaches, and interventions identified by the TAP that will advance recipients’ progress in meeting the goals of the initiative.