Opportunity Listing - Single Source Competition: Continuation of the Cardiovascular Repository for Type 1 Diabetes (CaRe-T1D) - Resource Center (U24 Clinical Trial Not Allowed)

Single Source Competition: Continuation of the Cardiovascular Repository for Type 1 Diabetes (CaRe-T1D) - Resource Center (U24 Clinical Trial Not Allowed)

Agency: National Institutes of Health

Assistance Listings: 93.847 -- Diabetes, Digestive, and Kidney Diseases Extramural Research

93.837 -- Cardiovascular Diseases Research

93.839 -- Blood Diseases and Resources Research

93.838 -- Lung Diseases Research

93.310 -- Trans-NIH Research Support

93.233 -- National Center on Sleep Disorders Research

93.840 -- Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders

Last Updated: June 4, 2026

View version history on Grants.gov

Description

This Notice of Funding Opportunity (NOFO) invites a single cooperative agreement application for the Resource Center for the Cardiovascular Repository for Type 1 Diabetes (CaRe-T1D). The purpose of CaRe-T1D is to support innovative, discovery and mechanistic research through the study of human cardiovascular (CV) tissue. This research seeks to better understand cardiovascular disease (CVD) in type 1 diabetes, highlight differences compared to type 2 diabetes, and ultimately guide the development of therapies to treat this major cause of morbidity and mortality for individuals with type 1 diabetes....

To achieve these goals, the Resource Center will expand the CaRe-T1D biorepository of human CV tissue, further develop the data commons for data sharing and for artificial intelligence (AI) tools, coordinate the research activities of the investigative teams in the CaRe-T1D consortium, and make CaRe-T1D resources accessible to the broader research community. This NOFO is associated with the Special Diabetes Program (https://www.niddk.nih.gov/about-niddk/research-areas/diabetes/type-1-diabetes-special-statutory-funding-program/about-special-diabetes-program) which funds research on the prevention, treatment, and cure of type 1 diabetes and its complications, including unique, innovative, and collaborative research consortia and clinical trials networks.This is a Notice of Funding Opportunity (NOFO) for a Single Source that will invite application(s) from eligible organization(s) to apply. Please see Section III. Eligibility for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.

Eligibility

Eligible applicants

Education

Independent school districts
Private institutions of higher education
Public and state institutions of higher education

Nonprofit

Nonprofits non-higher education with 501(c)(3)
Nonprofits non-higher education without 501(c)(3)
Other Native American tribal organizations

Business

For-profit organizations other than small businesses
Small businesses

Government

Federally recognized Native American tribal governments
County governments
State governments
City or township governments
Special district governments
Public and Indian housing authorities

Miscellaneous

Other

Additional information

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility. Only the following applicant is eligible to apply for this single source funding: University of Florida. Foreign Organizations/Foreign Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Grantor contact information

Description

NIDDK Division of Diabetes, Endocrinology and Metabolic Diseases NIDDK_DEM@nih.gov

Email

NIDDK_DEM@nih.gov

Documents

File name	Description	Last updated
RFA-DK-27-109-Full-Announcement.html	RFA-DK-27-109-Full-Announcement.html	Jun 4, 2026 03:05 PM UTC

Link to additional information

Closing: September 30, 2026

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$2,000,000

Program Funding

Expected awards

$--

Award Minimum

$1,500,000

Award Maximum

Funding opportunity number:

RFA-DK-27-109

Cost sharing or matching requirement:

Funding instrument type:

Cooperative agreement

Opportunity Category:

Discretionary

Opportunity Category Explanation:

Category of Funding Activity:

Health

Category Explanation:

History

Version:

Posted date:

June 4, 2026

Archive date:

November 29, 2026