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Avant Garde/Avenir Awards for Investigators Conducting High Risk/High Reward Research on HIV and Substance Use (or Substance Use Disorders) (DP1 Clinical Trial Optional)

Agency: National Institutes of Health

Assistance Listings
  • 93.279 -- Drug Use and Addiction Research Programs

Open opportunityLast Updated: Aug 27, 2026

Important dates

  • Closing: September 25, 2028

Award details

  • Expected project funding: Not specified
  • Expected awards: Not specified

Award min.

Not specified

Award max.

Not specified

  • Funding opportunity number:PAR-27-026
  • Cost sharing or matching requirement:No
  • Funding instrument type:
    • Grant
  • Opportunity Category:Discretionary
  • Opportunity Category Explanation:Not specified
  • Category of Funding Activity:
    • Health
  • Category Explanation:Not specified

History

  • Posted date: June 9, 2026
  • Archive date: November 24, 2028
  • Version: 2

View version history on Grants.gov

The purpose of this notice of funding opportunity (NOFO) is to support innovative basic, clinical, translational, and implementation science research relevant to HIV and substance use. This initiative encourages high risk high impact transformative studies that advance knowledge and strategies for HIV prevention, diagnosis, treatment and virus suppression in people who use substances and/or have a substance use disorder.

Eligibility

Business

  • For-profit organizations other than small businesses
  • Small businesses

Nonprofit

  • Nonprofits non-higher education without 501(c)(3)
  • Other Native American tribal organizations
  • Nonprofits non-higher education with 501(c)(3)

Education

  • Private institutions of higher education
  • Public and state institutions of higher education
  • Independent school districts

Government

  • Federally recognized Native American tribal governments
  • County governments
  • Special district governments
  • State governments
  • Public and Indian housing authorities
  • City or township governments

Miscellaneous

  • Other

Additional information on eligibility

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/Foreign Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Documents

File nameDescriptionLast updated
PAR-27-026-Revised-Full-Announcement.html
PAR-27-026-Revised-Full-Announcement.html
Aug 27, 2026 06:16 PM UTC

Agency contact information

Email: nidagmbemail@nida.nih.gov

nidagmbemail@nida.nih.gov

nidagmbemail@nida.nih.gov nidagmbemail@nida.nih.gov

Link to additional information

No additional information is available

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