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NINDS Efficacy and Exploratory Clinical Trials (UG3/UH3 - Clinical Trial Required)

Agency: National Institutes of Health

Assistance Listings: 93.853 -- Extramural Research Programs in the Neurosciences and Neurological Disorders

Last Updated: August 28, 2025

Description

The National Institute of Neurological Disorders and Stroke (NINDS) intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications for research on exploratory and efficacy clinical trials that address questions within the mission and research interests of the NINDS and may evaluate drugs, biologics, and devices, as well as surgical, behavioral and rehabilitation therapies.  Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the UG3/UH3 activity code. Investigators with expertise and insights into the mission and research interests of the NINDS, found at the NINDS website (https://www.ninds.nih.gov/), are encouraged to begin to consider applying for this new NOFO. 

Eligibility

Eligible applicants

Miscellaneous

  • Other

Education

  • Public and state institutions of higher education
  • Independent school districts
  • Private institutions of higher education

Government

  • City or township governments
  • County governments
  • Special district governments
  • Federally recognized Native American tribal governments
  • Public and Indian housing authorities
  • State governments

Business

  • For-profit organizations other than small businesses
  • Small businesses

Nonprofit

  • Nonprofits non-higher education without 501(c)(3)
  • Nonprofits non-higher education with 501(c)(3)
  • Other Native American tribal organizations

Additional information

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Grantor contact information

Description

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Email

Exploratory_Efficacy_Trials@ninds.nih.gov

Exploratory_Efficacy_Trials@ninds.nih.gov

Documents

No documents are currently available.

Link to additional information

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Forecasted

Estimated Post Date:

November 12, 2025

Estimated Application Due Date:

February 10, 2026

Estimated Due Date Description:

Not available

Estimated Award Date:

November 1, 2026

Estimated Project Start Date:

December 1, 2026

Fiscal Year:

2026

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$--

Program Funding

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Expected awards

$--

Award Minimum

$--

Award Maximum

Funding opportunity number:

PAR-26-069

Cost sharing or matching requirement:

No

Funding instrument type:

Cooperative agreement

Opportunity Category:

Discretionary

Opportunity Category Explanation:

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Category of Funding Activity:

Health

Category Explanation:

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History

Version:

1

Forecast posted date:

August 28, 2025

Archive date:

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