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Limited Competition: High Impact Specialized Innovation Programs in Clinical and Translational Science (Clinical Trials Optional)

Agency: National Institutes of Health

Assistance Listings: 93.350 -- National Center for Advancing Translational Sciences

Last Updated: March 9, 2026

Description

The purpose of the High Impact Specialized Innovation Programs (SIPs) is to support the development and demonstration of unique hub capabilities, research platforms and/or resources to address in a timely manner critical gap areas and/or roadblocks in clinical and translational science at awarded Clinical and Translational Science Awards (CTSA) Program Hubs. Successful programs supported through this funding opportunity are expected to lay a strong foundation for future adoption and/or dissemination of capabilities to additional CTSA Program Hubs.

Awards are made under the authorization of Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.

Eligibility

Eligible applicants

Miscellaneous

  • Other

Additional information

All applicant organizations and/or active award recipients for PAR-24-272 Clinical and Translational Science Award (UM1 Clinical Trial Optional) are eligible to apply for Specialized Innovation Programs (SIPs) under this NOFO. Only the primary UM1 CTSA program hub organization is eligible to apply (not partner or collaborator institutions).Companion optional applications may be submitted under the following scenarios:-concurrently with the UM1-while the UM1 application is under review consideration-after the UM1 application is funded-while the UM1 is under consideration for fundingApplications will only be awarded if there is an awarded UM1 application from the applicant organization.Other information on eligibility and number of applications:An active (not in an extension period) UM1 hub institution can submit up to two applications for SIPs per cycle as the primary institution.A CTSA UM1 hub may have up to two SIPs awards as the primary recipient at a given time.No more than two applications may be submitted by a UM1 hub as a primary per application due date and no more than two applications may be awarded to an active (not in an extension period) CTSA UM1 hub as a primary recipient, at a given time.A UM1 hub that is in an extension period is not allowed to submit an application as the primary institution unless a pending UM1 application has been submitted or is under review or funding consideration. Resubmission of a application without the required UM1 application is only allowed if the companion UM1 application is awarded.For the purpose of this NOFO, SIPs awarded in an extension period count towards the maximum of two SIP awards that may be awarded to an active UM1 hub as a primary, at a given time.

Grantor contact information

Description

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Email

CTSA Program Branch, Division of Clinical Innovation

RC2NOFO@nih.gov

Documents

No documents are currently available.

Link to additional information

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Forecasted

Estimated Post Date:

June 1, 2026

Estimated Application Due Date:

September 28, 2026

Estimated Due Date Description:

Not available

Estimated Award Date:

July 15, 2027

Estimated Project Start Date:

July 15, 2027

Fiscal Year:

2027

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

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Program Funding

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Expected awards

$--

Award Minimum

$--

Award Maximum

Funding opportunity number:

PAR-26-128

Cost sharing or matching requirement:

No

Funding instrument type:

Grant

Opportunity Category:

Discretionary

Opportunity Category Explanation:

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Category of Funding Activity:

Health

Category Explanation:

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History

Version:

1

Forecast posted date:

March 9, 2026

Archive date:

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