Opportunity Listing - Single Source: HeartShare 2.0: Refining Heart Failure Subtypes and Treatment Targets for Personalized Clinical Trials - Data Translation Center (U54 Clinical Trial Optional)

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Single Source: HeartShare 2.0: Refining Heart Failure Subtypes and Treatment Targets for Personalized Clinical Trials - Data Translation Center (U54 Clinical Trial Optional)

Agency: National Institutes of Health

Assistance Listings: 93.837 -- Cardiovascular Diseases Research

Last Updated: September 2, 2025

Description

The NHLBI intends to publish a Notice of Funding Opportunity (NOFO) to solicit a single application for the renewal of the Data Translation Center (DTC) for an ongoing NHLBI phenomics program, HeartShare. Pending submission and award of a meritorious peer-reviewed application, the DTC will coordinate the overall project, continue support of a cohort of patients with heart failure with preserved ejection fraction (HFpEF), and curate and analyze existing data from NIH cohorts and trials. Companion NOFO will support a Clinical Trial Center for new clinical trial activities and up to seven Clinical Centers (RFA-HL-26-026) that will recruit and retain heart failure patients.

style="margin-left:0in;">Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the U54 activity code. Investigators with expertise and insights into this area are encouraged to begin to consider applying for this NOFO. Grant authorities that allow NHLBI to forecast this opportunity are as follows: Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.

Eligibility

Eligible applicants

Miscellaneous

Other

Education

Public and state institutions of higher education

Additional information

This is a non-competitive funding opportunity intended, if the peer-reviewed application is meritorious, to fund a single award. Only the following applicant is eligible to apply for this single source funding: Northwestern University.

Grantor contact information

Description

Email

Division of Cardiovascular Sciences, HeartShare Team

nhlbiheartshare@mail.nih.gov

Documents

No documents are currently available.

Link to additional information

Forecasted

Estimated Post Date:

October 15, 2025

Estimated Application Due Date:

December 15, 2025

Estimated Due Date Description:

Not available

Estimated Award Date:

May 1, 2026

Estimated Project Start Date:

July 1, 2026

Fiscal Year:

2026

Application process

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Award

$--

Program Funding

Expected awards

$--

Award Minimum

$--

Award Maximum

Funding opportunity number:

RFA-HL-26-027

Cost sharing or matching requirement:

Funding instrument type:

Cooperative agreement

Opportunity Category:

Discretionary

Opportunity Category Explanation:

Category of Funding Activity:

Health

Category Explanation:

History

Version:

Forecast posted date:

September 2, 2025

Archive date: