Transformative Technologies for Experimental and Computational RNome Characterization and Functional Analysis
Agency: National Institutes of Health
Assistance Listings: 93.310 -- Trans-NIH Research Support
Description
The NIH Common Fund, in partnership with other NIH Institutes and Centers, plans to issue Notices of Funding Opportunity (NOFOs) for the RNomics program, which seeks to develop tools for studying the full set of RNA molecules (the RNome) in cells and tissues. The program will support technologies and resources that enable integrated analysis of RNA sequences, modifications, structures, locations, interactions, and functions to advance understanding of health and disease. RNomics includes four initiatives: technology enhancement centers, transformative technologies, molecular standards, and a coordinating center. Applications are not being solicited at this time. This notice is being provided to give potential applicants time to develop meaningful collaborations and strong projects.
This NOFO will support the transformative technologies initiative. These phased projects will develop new experimental and computational RNA technologies that address major limitations of current methods. Projects will focus on early-stage, high-risk ideas not yet demonstrated at scale or in biologically relevant systems. Priority areas include tools to sequence RNA, detect modifications, study RNA function, and analyze RNA across molecules, cells, and tissues. Projects that successfully complete Phase 1 milestones will be evaluated for transition to Phase 2. Phase 2 projects are expected to deliver validated tools for community use.
Eligibility
Eligible applicants
Government
- Special district governments
- County governments
- Federally recognized Native American tribal governments
- City or township governments
- Public and Indian housing authorities
- State governments
Business
- For-profit organizations other than small businesses
- Small businesses
Nonprofit
- Nonprofits non-higher education without 501(c)(3)
- Nonprofits non-higher education with 501(c)(3)
- Other Native American tribal organizations
Education
- Public and state institutions of higher education
- Independent school districts
- Private institutions of higher education
Miscellaneous
- Other
Additional information
Grantor contact information
Description
cfrnomics@od.nih.gov
Documents
No documents are currently available.
Link to additional information
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Forecasted
Estimated Post Date:
October 1, 2026
Estimated Application Due Date:
February 15, 2027
Estimated Due Date Description:
Not available
Estimated Award Date:
December 1, 2027
Estimated Project Start Date:
December 1, 2027
Fiscal Year:
2028
Award
$8,000,000
Program Funding
10
Expected awards
$--
Award Minimum
$500,000
Award Maximum
Funding opportunity number:
RFA-RM-28-006
Cost sharing or matching requirement:
Funding instrument type:
Cooperative agreement
Opportunity Category:
Discretionary
Opportunity Category Explanation:
Category of Funding Activity:
Health
Category Explanation:
History
Version:
1
Forecast posted date:
August 5, 2026
Archive date:
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