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Accelerating Research and Development of Next Generation Vaccines against Malaria - a Model for Mosquito-Borne Diseases (R61/R33 Clinical Trial Not Allowed)

Agency: National Institutes of Health

Assistance Listings
  • 93.855 -- Allergy and Infectious Diseases Research

Open opportunityLast Updated: Oct 13, 2026

View version history on Grants.gov

The purpose of this notice of funding opportunity (NOFO) is to support research and/or preclinical development of highly efficacious vaccines against malaria - one of the deadliest mosquito-borne diseases - by capitalizing on recent technological innovations, particularly in structure-based immunogen design, improved formulations, and combination vaccines. The goal is to achieve long-lasting, highly effective protection that can save lives, strengthen public health security in the United States, and serve as a model for, or are potentially effective against, other mosquito-borne diseases.   

Eligibility

Eligible applicants

Nonprofit

  • Nonprofits non-higher education without 501(c)(3)
  • Nonprofits non-higher education with 501(c)(3)
  • Other Native American tribal organizations

Government

  • Federally recognized Native American tribal governments
  • County governments
  • Special district governments
  • Public and Indian housing authorities
  • City or township governments
  • State governments

Education

  • Independent school districts
  • Private institutions of higher education
  • Public and state institutions of higher education

Business

  • Small businesses
  • For-profit organizations other than small businesses

Miscellaneous

  • Other

Additional information

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibilityForeign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.NIH will no longer issue awards (i.e., new, renewal, or non-competing continuation) to domestic or foreign entities that involve foreign subawards/subcontracts. All NIH-funded research involving foreign subawards/subcontracts must be submitted in response to a NOFO that is specifically designated for funded international collaborations. See NIH Grants Policy Statement 16.8 Collaborative International Research Awards.Applications involving foreign subawards/subcontracts submitted in response to this NOFO will be deemed noncompliant and will not be considered for funding. This policy applies to all monetary international collaborations resulting in foreign subawards/subcontracts, however, it does not preclude unfunded international collaborations or foreign components, funding for foreign consultants, or procurement of unique equipment or supplies from foreign vendors.

Grantor contact information

Description

Malaria and Other Mosquito Borne Diseases MalariaandOtherMosquitoBorneDiseases@mail.nih.gov

Email

MalariaandOtherMosquitoBorneDiseases@mail.nih.gov

MalariaandOtherMosquitoBorneDiseases@mail.nih.gov

Documents

File nameDescriptionLast updated
RFA-AI-28-024-Full-Announcement.html
RFA-AI-28-024-Full-Announcement.html
Oct 13, 2026 11:08 AM UTC

Link to additional information

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Closing: February 11, 2027

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$4,000,000

Program Funding

--

Expected awards

$--

Award Minimum

$--

Award Maximum

Funding opportunity number:

RFA-AI-28-024

Cost sharing or matching requirement:

No

Funding instrument type:

Grant

Opportunity Category:

Discretionary

Opportunity Category Explanation:

--

Category of Funding Activity:

Health

Category Explanation:

--

History

Version:

1

Posted date:

October 13, 2026

Archive date:

April 13, 2027

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