The National Institutes of Health (NIH) pursues its mission of seeking fundamental knowledge about the nature and behavior of living systems and the application of that knowledge to enhance health, lengthen life, and reduce illness and disability. Through this Notice of Funding Opportunity (NOFO), the participating NIH Institutes, Centers, and Offices (ICOs) encourage pursuit of that mission through the submission of investigator-initiated Program Project (P01) applications. With this Parent P01 NOFO, the NIH ICOs intend to support a broadly based, multidisciplinary, often long-term research program with a specific major scientific objective or theme. The proposed Program Project must be related to the programmatic interests of one or more of the participating ICOs based on their scientific missions. Each application submitted in response to this NOFO must consist of at least two research projects and an administrative core. Additionally, a P01 application may include scientific cores, if needed for the proposed research. The projects included within the Program must share a common central scientific theme, focus, and/or an overall objective. Statutory authority: Awards are made under the authorization of Sections 301 and 405 of the Public Health Service Act as amended (42 USC 241 and 284) and under Federal Regulations 42 CFR Part 52 and 2 CFR Part 200.

Government

• Federally recognized Native American tribal governments
• State governments
• Special district governments
• Public and Indian housing authorities
• County governments
• City or township governments

Education

• Public and state institutions of higher education
• Independent school districts
• Private institutions of higher education

Nonprofit

• Nonprofits non-higher education with 501(c)(3)
• Nonprofits non-higher education without 501(c)(3)
• Other Native American tribal organizations

Business

• For-profit organizations other than small businesses
• Small businesses

Miscellaneous

• Other