Countering Weapons of Mass Destruction: Academic Research Initiative (ARI)

Objectives

The ARI Program has two primary objectives: 1) Engage the academic community to advance fundamental knowledge for CBRN sciences applicable to Countering Weapons of Mass Destruction (CWMD) with emphasis on fundamental research to solve long-term, high-risk challenges; and 2) Develop human capital for the CBRN science and engineering professions. Furthermore, the program works to sustain a long-term commitment to basic research in these fields and coordinates research efforts across the federal government. 

Priorities

Each grant application will be evaluated based on the criteria provided in Evaluation Criteria under the Application Review Information section. The research topics in this announcement will address technical challenges in order to enable increased capability to detect, identify, and notify about CBRN threats. The full solicitation research topics are listed in Appendix A. Summaries of the topics are as follows:

·        Topic Area 1 (TA-01): MicroRNA as Biomarkers for Early Biothreat Detection: Improve the understanding of microRNA (miRNA) as a tool in early detection and diagnosis of biothreats. Focus areas may include research on how changes in miRNA packaging and/or expression levels can affect miRNA functionality, as well as whether individuals or animals exposed to biological agents have different expression profiles of circulating serum miRNA compared with controls. Research should seek to use miRNA expression profiles towards development of early prediction, detection, diagnosis, and/or monitoring methods, of biothreats with focus on biological agents of security concern.

·        Topic Area 2 (TA-02): Chemical, Biological, or Radiological/Nuclear (CBRN) Area Detection and Analytics: Develop a broad-area sensing array approach for CBRN threat detection and tracking before, during, and after a high-profile event. Collect baseline data for application of analytical tools, during the present project and for future efforts. Develop methods to detect and remediate induced bias in threat detection algorithms.

·        Topic Area 3 (TA-03): Technology Component Improvement for Neutron-Based Active Interrogation: Develop advanced technology components for improvements of active interrogation systems using neutrons to detect threats such as special nuclear material (SNM), explosives, and illicit drugs for DHS applications. Focus areas may include: detection algorithms; specific software tools to support the detection algorithm; simulation and detection studies to inform advanced detector implementation; studies of threat material signatures; or determination of neutron source requirements.