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Shared Instrumentation Grant (SIG) Program (S10 Clinical Trial Not Allowed)

Agency: National Institutes of Health

Assistance Listings: 93.351 -- Research Infrastructure Programs

Last Updated: September 8, 2025

Description

This Notice of Funding Opportunity (NOFO) announces the restructured Shared Instrumentation Grant (SIG) Program that consolidates three existing shared-use instrumentation programs, i.e., the Shared Instrumentation Grant program, the High-End Instrumentation Grant program, and the Basic Instrumentation Grant program. The NOFO invites applications from groups of NIH-supported investigators to purchase or upgrade a single item of state-of-the-art commercially available instrument or an integrated instrumentation system. The instruments purchased through the SIG Program require to be optimally shared among the users to ensure efficient and cost-effective research operations, enable rigorous and reproducible measurements, and encourage collaborative research and benefit broad research communities at large. The minimum award is $300,000. There is no cap on total cost of the instrument; however, the maximum award is $5,000,000. Cost sharing is required for premium instruments or special use instruments. 

Eligibility

Eligible applicants

Nonprofit

  • Nonprofits non-higher education with 501(c)(3)
  • Nonprofits non-higher education without 501(c)(3)

Education

  • Private institutions of higher education
  • Public and state institutions of higher education

Additional information

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Grantor contact information

Description

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Email

xiang-ning.li@nih.gov

xiang-ning.li@nih.gov

Documents

No documents are currently available.

Link to additional information

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Forecasted

Estimated Post Date:

December 12, 2025

Estimated Application Due Date:

July 1, 2026

Estimated Due Date Description:

Not available

Estimated Award Date:

March 1, 2027

Estimated Project Start Date:

March 1, 2027

Fiscal Year:

2027

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$83,000,000

Program Funding

102

Expected awards

$300,000

Award Minimum

$5,000,000

Award Maximum

Funding opportunity number:

PAR-26-070

Cost sharing or matching requirement:

Yes

Funding instrument type:

Grant

Opportunity Category:

Discretionary

Opportunity Category Explanation:

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Category of Funding Activity:

Health

Category Explanation:

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History

Version:

1

Forecast posted date:

September 8, 2025

Archive date:

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