New Generation of Glucose Control Technologies Incorporating AI/ML Tools/Strategies (R01 - Clinical Trial Optional)
Agency: National Institutes of Health
Assistance Listings: 93.847 -- Diabetes, Digestive, and Kidney Diseases Extramural Research
Last Updated: May 13, 2026
Description
The purpose of this funding opportunity is to support research addressing barriers that limit progress toward more effective open- and closed-loop diabetes control systems. This may include research that addresses: 1) innovation of sensing relevant analytes/physiologic signals; 2) novel formulation and delivery of hormones; 3) artificial intelligence (AI)/machine learning (ML)-driven tools/algorithms; and 4) digital twin modeling to augment decision support and automated control systems with the goal of improving glycemic control, reducing burden of care, and enhancing quality of life of people...
with T1D].This NOFO is associated with the Special Diabetes Program (https://www.niddk.nih.gov/about-niddk/research-areas/diabetes/type-1-diabetes-special-statutory-funding-program/about-special-diabetes-program) which funds research on the prevention, treatment, and cure of type 1 diabetes and its complications, including unique, innovative, and collaborative research consortia and clinical trials networks
Eligibility
Eligible applicants
Government
- Public and Indian housing authorities
- Federally recognized Native American tribal governments
- State governments
- City or township governments
- Special district governments
- County governments
Business
- Small businesses
- For-profit organizations other than small businesses
Nonprofit
- Other Native American tribal organizations
- Nonprofits non-higher education without 501(c)(3)
- Nonprofits non-higher education with 501(c)(3)
Education
- Public and state institutions of higher education
- Private institutions of higher education
- Independent school districts
Miscellaneous
- Other
Additional information
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Grantor contact information
Description
Division of Diabetes, Endocrinology and Metabolic Diseases
NIDDK_DEM@nih.gov
NIDDK_DEM@nih.gov
Documents
| File name | Description | Last updated |
|---|---|---|
| RFA-DK-27-146-Full-Announcement.html | RFA-DK-27-146-Full-Announcement.html | May 7, 2026 06:24 PM UTC |
Link to additional information
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Closing: June 17, 2026
Award
$3,000,000
Program Funding
5
Expected awards
$--
Award Minimum
$500,000
Award Maximum
Funding opportunity number:
RFA-DK-27-146
Cost sharing or matching requirement:
No
Funding instrument type:
Grant
Opportunity Category:
Discretionary
Opportunity Category Explanation:
--
Category of Funding Activity:
Health
Category Explanation:
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History
Version:
1
Posted date:
May 7, 2026
Archive date:
August 16, 2026
