·        The HSRA will support health services research approaches that include comparative effectiveness research; implementation of interventions, diagnostics and clinical practices/guidelines; and validation of data science insights.

·        Applications must include clinical research or clinical trials. Prospective or retrospective clinical research or clinical trials involving human subjects, human subject data/records, and human anatomical substances are allowed.

·        Preliminary data are required.

·        Basic, preclinical and animal research are prohibited.

·        For research prospectively enrolling human subjects, inclusion of community-based participatory research (CBPR) approaches is required.

·        Early-Career Investigator Partnering Option: This option accommodates two Principal Investigators (PIs), one of which is an Early-Career Investigator. If recommended for funding, each PI will receive a separate award.