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Innovative Molecular and Cellular Analysis Technologies for Basic and Clinical Cancer Research (R61 Clinical Trial Not Allowed)

Agency: National Institutes of Health

Assistance Listings: 93.394 -- Cancer Detection and Diagnosis Research

Last Updated: December 9, 2025

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) solicits grant applications proposing exploratory research projects focused on the early-stage development of highly innovative technologies offering novel molecular or cellular analysis capabilities for basic or clinical cancer research. The emphasis of this NOFO is on supporting the development of novel capabilities involving a high degree of technical innovation for targeting, probing, or assessing molecular and cellular features of cancer biology. Technologies proposed for development may be intended to have widespread applicability but must be focused on improving molecular and/or cellular characterizations of cancer biology. Well-suited applications must offer the potential to accelerate and/or enhance research in the areas of cancer biology, early detection and screening, clinical diagnosis, treatment, control, or epidemiology, and/or address issues associated with cancer health disparities.This funding opportunity is part of a broader NCI-sponsored Innovative Molecular Analysis Technologies (IMAT) Program.

Eligibility

Eligible applicants

Education

  • Independent school districts
  • Public and state institutions of higher education
  • Private institutions of higher education

Nonprofit

  • Nonprofits non-higher education with 501(c)(3)
  • Other Native American tribal organizations
  • Nonprofits non-higher education without 501(c)(3)

Government

  • County governments
  • State governments
  • Federally recognized Native American tribal governments
  • Public and Indian housing authorities
  • City or township governments
  • Special district governments

Business

  • For-profit organizations other than small businesses
  • Small businesses

Miscellaneous

  • Other

Additional information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Documents

File nameDescriptionLast updated
RFA-CA-25-001-Full-Announcement.html
RFA-CA-25-001 Full Announcement Text
Dec 16, 2024 04:28 PM UTC

Link to additional information

https://grants.nih.gov/grants/guide/rfa-files/RFA-CA-25-001.html

Archived: February 7, 2026

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$150,000

Program Funding

17

Expected awards

$--

Award Minimum

$150,000

Award Maximum

Funding opportunity number:

RFA-CA-25-001

Cost sharing or matching requirement:

No

Funding instrument type:

Grant

Opportunity Category:

Discretionary

Opportunity Category Explanation:

--

Category of Funding Activity:

Education

Health

Category Explanation:

--

History

Version:

2

Posted date:

December 16, 2024

Archive date:

February 7, 2026

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