NIH Director’s Transformative Research Award for Individual and Group Science (R01 Clinical Trial Optional)
Agency: National Institutes of Health
Assistance Listings
- 93.310 -- Trans-NIH Research Support
Archived opportunityLast Updated: Jun 29, 2026
Important dates
- Archived: November 2, 2026
- Closed: September 3, 2026
Award details
- Expected project funding: $8,000,000
- Expected awards: 7
Award min.
Not specified
Award max.
Not specified
- Funding opportunity number:RFA-RM-27-003
- Cost sharing or matching requirement:No
- Funding instrument type:
- Grant
- Opportunity Category:Discretionary
- Opportunity Category Explanation:Not specified
- Category of Funding Activity:
- Health
- Category Explanation:Not specified
History
- Posted date: June 29, 2026
- Archive date: November 2, 2026
- Version: 1
Summary
Jump to documentsThe NIH Director"s Transformative Research Award supports individual scientists or groups of scientists proposing bold, groundbreaking, exceptionally innovative, original, and/or unconventional research with the potential to create new scientific paradigms, establish entirely new and improved clinical approaches, or develop transformative technologies. Applications in any area within the biomedical sciences are welcome; topics may involve basic, translational, or clinical research. No preliminary data are required. Projects must clearly demonstrate, based on the strength of the logic, a compelling...
potential to produce a major impact in a broad area of relevance to the NIH. The NIH Director"s Transformative Research Award is a component of the High-Risk, High-Reward Research (HRHR) program of the NIH Common Fund.
Eligibility
Government
- Special district governments
- City or township governments
- State governments
- Public and Indian housing authorities
- Federally recognized Native American tribal governments
- County governments
Nonprofit
- Nonprofits non-higher education with 501(c)(3)
- Nonprofits non-higher education without 501(c)(3)
- Other Native American tribal organizations
Business
- Small businesses
- For-profit organizations other than small businesses
Education
- Public and state institutions of higher education
- Private institutions of higher education
- Independent school districts
Miscellaneous
- Other
Additional information on eligibility
Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.
Documents
| File name | Description | Last updated |
|---|---|---|
| RFA-RM-27-003-Full-Announcement.html | RFA-RM-27-003-Full-Announcement.html | Jun 29, 2026 12:19 PM UTC |
Agency contact information
Email: Transformative_Awards@mail.nih.gov
Transformative_Awards@mail.nih.gov
NIH Director's Transformative Research Award Program
Transformative_Awards@mail.nih.gov
Link to additional information
No additional information is available
