Grand Opportunity in Medications Development for Substance-Use Disorders (U01 Clinical Trial Optional)
Agency: National Institutes of Health
Assistance Listings: 93.279 -- Drug Use and Addiction Research Programs
Description
The purpose of this notice of Funding Opportunity (NOFO) is to accelerate the development of medication for the treatment of Substance Use Disorders (SUDs) by encouraging research applications to support a broad array of preclinical and/or clinical research projects. The goal is to fund medication studies that will have high impact and quickly yield the necessary results to advance medications closer to FDA approval. It is expected that these U01s will be short-term (funded for up to 3 years) and large (up to $5 million per year) cooperative agreements with close monitoring and significant scientific involvement of NIDA staff. This funding opportunity will enable critical medications development studies that would not be feasible using the traditional R01 activity code.
Eligibility
Eligible applicants
Government
- County governments
- Federally recognized Native American tribal governments
- State governments
- Special district governments
- City or township governments
- Public and Indian housing authorities
Education
- Public and state institutions of higher education
- Independent school districts
- Private institutions of higher education
Miscellaneous
- Other
Business
- Small businesses
- For-profit organizations other than small businesses
Nonprofit
- Other Native American tribal organizations
- Nonprofits non-higher education with 501(c)(3)
- Nonprofits non-higher education without 501(c)(3)
Additional information
Grantor contact information
Description
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
Documents
File name | Description | Last updated |
---|---|---|
PAR-25-328-Full-Announcement.html | PAR-25-328 Full Announcement Text | Jan 3, 2025 03:19 PM UTC |
Link to additional information
https://grants.nih.gov/grants/guide/pa-files/PAR-25-328.html
Closed: August 11, 2025
Award
$--
Program Funding
--
Expected awards
$--
Award Minimum
$5,000,000
Award Maximum
Funding opportunity number:
PAR-25-328
Cost sharing or matching requirement:
Funding instrument type:
Cooperative agreement
Opportunity Category:
Discretionary
Opportunity Category Explanation:
Category of Funding Activity:
Education
Health
Category Explanation:
History
Version:
2
Posted date:
January 3, 2025
Archive date:
September 16, 2025