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Trailblazer Award for New and Early Stage Investigators (R21 Clinical Trial Optional)

Agency: National Institutes of Health

Assistance Listings
  • 93.866 -- Aging Research
  • 93.393 -- Cancer Cause and Prevention Research
  • 93.543 -- Vision Research - Research Projects
  • 93.310 -- Trans-NIH Research Support
  • 93.399 -- Cancer Control
  • 93.394 -- Cancer Detection and Diagnosis Research
  • 93.213 -- Research and Training in Complementary and Integrative Health
  • 93.396 -- Cancer Biology Research
  • 93.313 -- NIH Office of Research on Women's Health
  • 93.113 -- Environmental Health
  • 93.143 -- NIEHS Superfund Hazardous Substances_Basic Research and Education
  • 93.480 -- Complementary and Integrative Health - SBIR/STTR
  • 93.395 -- Cancer Treatment Research
  • 93.121 -- Oral Diseases and Disorders Research
  • 93.286 -- Discovery and Applied Research for Technological Innovations to Improve Human Health

Archived opportunityLast Updated: Oct 26, 2026

View version history on Grants.gov

Description

This Trailblazer Award is an opportunity for NIH-defined New and Early Stage Investigators (https://grants.nih.gov/policy/early-investigators/index.htm) to pursue research programs that integrate engineering and the physical sciences with the life and/or biomedical sciences. A Trailblazer project may be exploratory, developmental, proof of concept, or high risk-high impact, and may be technology design-directed, discovery-driven, or hypothesis-driven. Importantly, applicants must propose research approaches for which there are minimal or no preliminary data.

Eligibility

Eligible applicants

Business

  • For-profit organizations other than small businesses
  • Small businesses

Government

  • City or township governments
  • Special district governments
  • County governments
  • Public and Indian housing authorities
  • State governments
  • Federally recognized Native American tribal governments

Education

  • Independent school districts
  • Public and state institutions of higher education
  • Private institutions of higher education

Nonprofit

  • Other Native American tribal organizations
  • Nonprofits non-higher education with 501(c)(3)
  • Nonprofits non-higher education without 501(c)(3)

Miscellaneous

  • Other

Additional information

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Grantor contact information

Description

NIBIB_R21 Please contact via e-mail

Email

NIBIB_R21@nih.gov

NIBIB_R21@nih.gov

Documents

No documents are currently available.

Link to additional information

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Archived: October 27, 2026

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$--

Program Funding

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Expected awards

$--

Award Minimum

$--

Award Maximum

Funding opportunity number:

PAR-27-120

Cost sharing or matching requirement:

No

Funding instrument type:

Grant

Opportunity Category:

Discretionary

Opportunity Category Explanation:

--

Category of Funding Activity:

Health

Category Explanation:

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History

Version:

3

Posted date:

June 11, 2025

Archive date:

October 27, 2026

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