Opportunity Listing - Development and Testing of Novel Interventions to Improve HIV Prevention, Treatment, and Program Implementation for People Who Use Substances (R34 Clinical Trial Required)

Development and Testing of Novel Interventions to Improve HIV Prevention, Treatment, and Program Implementation for People Who Use Substances (R34 Clinical Trial Required)

Agency: National Institutes of Health

Assistance Listings: 93.279 -- Drug Use and Addiction Research Programs

Last Updated: January 28, 2026

Description

This notice of funding opportunity (NOFO) encourages formative research, intervention development, and pilot-testing of interventions. Primary scientific areas of focus include the feasibility, tolerability, acceptability and safety of novel or adapted interventions that target HIV prevention, treatment or services research for people who use drugs. For the purposes of this NOFO, "intervention" may include behavioral, social, or structural approaches, as well as combination biomedical and behavioral approaches that prevent the acquisition and transmission of HIV infection, or improve clinical outcomes for persons living with HIV.

Eligibility

Eligible applicants

Government

Special district governments
County governments
City or township governments
Federally recognized Native American tribal governments
State governments
Public and Indian housing authorities

Nonprofit

Nonprofits non-higher education with 501(c)(3)
Other Native American tribal organizations
Nonprofits non-higher education without 501(c)(3)

Business

For-profit organizations other than small businesses
Small businesses

Miscellaneous

Other

Education

Independent school districts
Public and state institutions of higher education
Private institutions of higher education

Additional information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Documents

File name	Description	Last updated
PAR-24-329-Full-Announcement.html	PAR-24-329 Full Announcement Text	Jan 8, 2025 09:55 PM UTC

Link to additional information

https://grants.nih.gov/grants/guide/pa-files/PAR-24-329.html

Closing: May 7, 2026

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$--

Program Funding

Expected awards

$--

Award Minimum

$--

Award Maximum

Funding opportunity number:

PAR-24-329

Cost sharing or matching requirement:

Funding instrument type:

Grant

Opportunity Category:

Discretionary

Opportunity Category Explanation:

Category of Funding Activity:

Education

Health

Category Explanation:

History

Version:

Posted date:

January 8, 2025

Archive date:

July 6, 2026