Opportunity Listing - BRAIN Initiative: Theories, Models and Methods for Analysis of Complex Data from the Brain (R01 Clinical Trial Not Allowed)

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BRAIN Initiative: Theories, Models and Methods for Analysis of Complex Data from the Brain (R01 Clinical Trial Not Allowed)

Agency: National Institutes of Health

Assistance Listings: 93.279 -- Drug Use and Addiction Research Programs

93.173 -- Research Related to Deafness and Communication Disorders

93.867 -- Vision Research

93.286 -- Discovery and Applied Research for Technological Innovations to Improve Human Health

93.242 -- Mental Health Research Grants

93.273 -- Alcohol Research Programs

93.213 -- Research and Training in Complementary and Integrative Health

93.865 -- Child Health and Human Development Extramural Research

93.866 -- Aging Research

93.853 -- Extramural Research Programs in the Neurosciences and Neurological Disorders

93.372 -- 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies

Last Updated: September 16, 2025

View version history on Grants.gov

Description

The Theories, Models and Methods (TMM) initiative will support the development of computational tools for understanding dynamic brain circuits that are made broadly accessible to the greater research community. This program supports applications focused on tool building and dissemination in the domain of theories about neural circuit mechanisms, models of circuit structure and function, and/or computational methods of analysis spanning across scales from neurons to behavior. The development of novel theories, computational models and methods for understanding brain function will help characterize...

fundamental principles of brain function and organization, characterize cellular and circuit-level neural computations over time in different regions, and understand how interactions of multiple brain circuits enable flexible behaviors and contribute to brain-wide neural dynamics. These tools will be critical for developing treatments such as closed loop systems for brain disorders including Parkinsons disease and major depressive disorder.

Eligibility

Eligible applicants

Nonprofit

Nonprofits non-higher education with 501(c)(3)
Nonprofits non-higher education without 501(c)(3)
Other Native American tribal organizations

Government

State governments
City or township governments
Special district governments
Public and Indian housing authorities
County governments
Federally recognized Native American tribal governments

Education

Private institutions of higher education
Public and state institutions of higher education
Independent school districts

Miscellaneous

Other

Business

For-profit organizations other than small businesses
Small businesses

Additional information

Other Eligible Applicants include the following: Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; U.S. Territory or Possession.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Documents

File name	Description	Last updated
RFA-DA-27-004-Full-Announcement.html	RFA-DA-27-004 Full Announcement Text	Sep 16, 2025 06:27 PM UTC

Link to additional information

https://grants.nih.gov/grants/guide/rfa-files/RFA-DA-27-004.html

Closing: November 8, 2027

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$--

Program Funding

Expected awards

$--

Award Minimum

$--

Award Maximum

Funding opportunity number:

RFA-DA-27-004

Cost sharing or matching requirement:

Funding instrument type:

Grant

Opportunity Category:

Discretionary

Opportunity Category Explanation:

Category of Funding Activity:

Education

Health

Income security and social services

Category Explanation:

History

Version:

Posted date:

September 16, 2025

Archive date:

December 14, 2027