BRAIN Initiative: Theories, Models and Methods for Analysis of Complex Data from the Brain (R01 Clinical Trial Not Allowed)
Agency: National Institutes of Health
Assistance Listings
- 93.279 -- Drug Use and Addiction Research Programs
- 93.173 -- Research Related to Deafness and Communication Disorders
- 93.867 -- Vision Research
- 93.286 -- Discovery and Applied Research for Technological Innovations to Improve Human Health
- 93.242 -- Mental Health Research Grants
- 93.273 -- Alcohol Research Programs
- 93.213 -- Research and Training in Complementary and Integrative Health
- 93.865 -- Child Health and Human Development Extramural Research
- 93.866 -- Aging Research
- 93.853 -- Extramural Research Programs in the Neurosciences and Neurological Disorders
- 93.372 -- 21st Century Cures Act - Brain Research through Advancing Innovative Neurotechnologies
Open opportunityLast Updated: May 13, 2026
Important dates
- Closing: November 8, 2027
Award details
- Expected project funding: Not specified
- Expected awards: Not specified
Award min.
Not specified
Award max.
Not specified
- Funding opportunity number:RFA-DA-27-004
- Cost sharing or matching requirement:No
- Funding instrument type:
- Grant
- Opportunity Category:Discretionary
- Opportunity Category Explanation:Not specified
- Category of Funding Activity:
- Education
- Health
- Income security and social services
- Category Explanation:Not specified
History
- Posted date: September 16, 2025
- Archive date: December 14, 2027
- Version: 1
Summary
Jump to documentsThe Theories, Models and Methods (TMM) initiative will support the development of computational tools for understanding dynamic brain circuits that are made broadly accessible to the greater research community. This program supports applications focused on tool building and dissemination in the domain of theories about neural circuit mechanisms, models of circuit structure and function, and/or computational methods of analysis spanning across scales from neurons to behavior. The development of novel theories, computational models and methods for understanding brain function will help characterize...
fundamental principles of brain function and organization, characterize cellular and circuit-level neural computations over time in different regions, and understand how interactions of multiple brain circuits enable flexible behaviors and contribute to brain-wide neural dynamics. These tools will be critical for developing treatments such as closed loop systems for brain disorders including Parkinsons disease and major depressive disorder.
Eligibility
Nonprofit
- Nonprofits non-higher education with 501(c)(3)
- Nonprofits non-higher education without 501(c)(3)
- Other Native American tribal organizations
Government
- State governments
- City or township governments
- Special district governments
- Public and Indian housing authorities
- County governments
- Federally recognized Native American tribal governments
Education
- Private institutions of higher education
- Public and state institutions of higher education
- Independent school districts
Miscellaneous
- Other
Business
- For-profit organizations other than small businesses
- Small businesses
Additional information on eligibility
Other Eligible Applicants include the following:
Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; U.S. Territory or Possession.
Documents
| File name | Description | Last updated |
|---|---|---|
| RFA-DA-27-004-Full-Announcement.html | RFA-DA-27-004 Full Announcement Text | Sep 16, 2025 06:27 PM UTC |
Agency contact information
Email: grantsinfo@nih.gov
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
NIH Grants Information
grantsinfo@nih.gov
