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Maximizing Investigators’ Research Award (MIRA) for Early Stage Investigators (ESI)

Agency: National Institutes of Health

Assistance Listings: 93.859 -- Biomedical Research and Research Training

Last Updated: September 15, 2025

Description

NIGMS intends to continue its flagship Maximizing Investigators' Research Awards (MIRA) program for Early Stage Investigators (ESIs). Over the past decade, MIRA has become the primary approach through which NIGMS supports fundamental, investigator-initiated research. MIRA provides support for research in an investigator's laboratory that falls within the mission of NIGMS through a single grant award.  It provides investigators with greater funding stability and scientific flexibility, enabling researchers to take on more ambitious and innovative studies, enhancing scientific productivity and the chances for important breakthroughs. It also reduces administrative burden by combining all NIGMS research support for a PI into a single award. The program is structured to distribute funds widely among the nation's highly talented and promising early career investigators.  

Eligibility

Eligible applicants

Government

  • Special district governments
  • Federally recognized Native American tribal governments
  • State governments
  • County governments
  • City or township governments
  • Public and Indian housing authorities

Nonprofit

  • Other Native American tribal organizations
  • Nonprofits non-higher education with 501(c)(3)
  • Nonprofits non-higher education without 501(c)(3)

Miscellaneous

  • Other

Education

  • Independent school districts
  • Private institutions of higher education
  • Public and state institutions of higher education

Business

  • For-profit organizations other than small businesses
  • Small businesses

Additional information

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;

Grantor contact information

Description

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Email

ESIMIRA@nigms.nih.gov

ESIMIRA@nigms.nih.gov

Documents

No documents are currently available.

Link to additional information

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Forecasted

Estimated Post Date:

March 1, 2026

Estimated Application Due Date:

October 5, 2026

Estimated Due Date Description:

Not available

Estimated Award Date:

July 1, 2027

Estimated Project Start Date:

July 1, 2027

Fiscal Year:

2027

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$--

Program Funding

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Expected awards

$--

Award Minimum

$--

Award Maximum

Funding opportunity number:

PAR-26-032

Cost sharing or matching requirement:

No

Funding instrument type:

Grant

Opportunity Category:

Discretionary

Opportunity Category Explanation:

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Category of Funding Activity:

Health

Category Explanation:

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History

Version:

1

Forecast posted date:

September 15, 2025

Archive date:

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