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Translational Research in Maternal and Pediatric Pharmacology and Therapeutics (R21 Clinical Trial Optional)

Agency: National Institutes of Health

Assistance Listings: 93.865 -- Child Health and Human Development Extramural Research

93.279 -- Drug Use and Addiction Research Programs

93.855 -- Allergy and Infectious Diseases Research

93.313 -- NIH Office of Research on Women's Health

Last Updated: March 31, 2025

The purpose of this notice of funding opportunity (NOFO) is to support translational and clinical research to (1) advance precision medicine in pregnant women, lactating women, and children through the development of novel tools, models, and other technologies that could have a direct clinical or health impact; (2) enhance the understanding of the underlying mechanisms of drug action, including the role of pediatric ontogeny and the dynamic physiological changes that occur during pregnancy and lactation; and (3) discover and develop novel therapeutics or enhance the usage of existing drugs or drug repurposing for safer and more effective medications in pregnant and lactating women, neonates, and children. The overall goal is to improve safe and effective precision therapeutics for pregnant and lactating women, fetuses, neonates, and children, including those with disabilities.

Eligibility

Eligible applicants

Government

  • State governments
  • Federally recognized Native American tribal governments
  • Public and Indian housing authorities
  • City or township governments
  • Special district governments
  • County governments

Education

  • Independent school districts
  • Public and state institutions of higher education
  • Private institutions of higher education

Business

  • For-profit organizations other than small businesses
  • Small businesses

Miscellaneous

  • Other

Nonprofit

  • Other Native American tribal organizations
  • Nonprofits non-higher education without 501(c)(3)
  • Nonprofits non-higher education with 501(c)(3)

Additional information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Documents

File nameDescriptionLast updated
PAR-25-111-Full-Announcement.html
PAR-25-111 Full Announcement Text
Nov 18, 2024 07:10 PM UTC

Link to additional information

https://grants.nih.gov/grants/guide/pa-files/PAR-25-111.html

Closing: May 7, 2026

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$--

Program Funding

--

Expected awards

$--

Award Minimum

$--

Award Maximum

Funding opportunity number:

PAR-25-111

Cost sharing or matching requirement:

No

Funding instrument type:

Grant

Opportunity Category:

Discretionary

Opportunity Category Explanation:

--

Category of Funding Activity:

Health

Income security and social services

Education

Category Explanation:

--

History

Version:

2

Posted date:

November 18, 2024

Archive date:

June 12, 2026

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