Opportunity Listing - Elucidating Immunometabolic Responses to HIV Infection that Increase TB or HBV Risk (R01 Clinical Trial Not Allowed)

Elucidating Immunometabolic Responses to HIV Infection that Increase TB or HBV Risk (R01 Clinical Trial Not Allowed)

Agency: National Institutes of Health

Assistance Listings: 93.855 -- Allergy and Infectious Diseases Research

Last Updated: May 13, 2026

Description

The purpose of this notice of funding opportunity (NOFO) is to support research to elucidate how HIV-induced immunometabolic alterations, in a host suppressed on combination antiretroviral therapy (cART-suppressed), impact the immune response and increase risk for poor outcomes due to a second, potentially long-term, infection such as Mycobacterium tuberculosis (Mtb) or hepatitis B virus (HBV). This NOFO aims to support research to define how HIV-driven alterations to immunometabolism affect immune cell regulation, cell-cell interactions, response to treatment, and, ultimately, tuberculosis (TB) and HBV disease progression.

Eligibility

Eligible applicants

Business

For-profit organizations other than small businesses
Small businesses

Nonprofit

Nonprofits non-higher education without 501(c)(3)
Other Native American tribal organizations
Nonprofits non-higher education with 501(c)(3)

Government

County governments
Public and Indian housing authorities
Federally recognized Native American tribal governments
State governments
Special district governments
City or township governments

Miscellaneous

Other

Education

Independent school districts
Private institutions of higher education
Public and state institutions of higher education

Additional information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Documents

File name	Description	Last updated
PAR-25-315-Full-Announcement.html	PAR-25-315 Full Announcement Text	Dec 18, 2024 07:57 PM UTC

Link to additional information

https://grants.nih.gov/grants/guide/pa-files/PAR-25-315.html

Archived: March 20, 2026

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$--

Program Funding

Expected awards

$--

Award Minimum

$--

Award Maximum

Funding opportunity number:

PAR-25-315

Cost sharing or matching requirement:

Funding instrument type:

Grant

Opportunity Category:

Discretionary

Opportunity Category Explanation:

Category of Funding Activity:

Health

Category Explanation:

History

Version:

Posted date:

December 18, 2024

Archive date:

March 20, 2026