Opportunity Listing - HEAL Initiative: Prevention and Management of Chronic Pain in Rural Populations (UG3/UH3, Clinical Trials Required)

HEAL Initiative: Prevention and Management of Chronic Pain in Rural Populations (UG3/UH3, Clinical Trials Required)

Agency: National Institutes of Health

Assistance Listings: 93.838 -- Lung Diseases Research

93.233 -- National Center on Sleep Disorders Research

93.361 -- Nursing Research

93.865 -- Child Health and Human Development Extramural Research

93.839 -- Blood Diseases and Resources Research

93.279 -- Drug Abuse and Addiction Research Programs

93.840 -- Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders

93.866 -- Aging Research

93.393 -- Cancer Cause and Prevention Research

93.273 -- Alcohol Research Programs

93.395 -- Cancer Treatment Research

93.853 -- Extramural Research Programs in the Neurosciences and Neurological Disorders

93.307 -- Minority Health and Health Disparities Research

93.837 -- Cardiovascular Diseases Research

93.213 -- Research and Training in Complementary and Integrative Health

93.846 -- Arthritis, Musculoskeletal and Skin Diseases Research

93.121 -- Oral Diseases and Disorders Research

Last Updated: May 13, 2026

View version history on Grants.gov

Description

This Funding Opportunity Announcement (FOA) encourages UG3/UH3 phased cooperative research applications to accelerate implementation of effective non-opioid interventions for chronic pain management in rural and remote populations. Projects include pragmatic, implementation, or hybrid effectiveness-implementation trials to improve pain management and reduce the use of inappropriate opioid medications. Awards made under this FOA will initially support a milestone-driven, planning phase (UG3) of 1 to 2 years, with possible transition to an implementation phase (UH3) of up to 4 years duration (5 years...

total for the two phases). UG3 projects that have met the scientific milestone and feasibility requirements may transition to the UH3 phase. The UG3/UH3 application must be submitted as a single application, following the instructions described in this FOA. The overall goal of this initiative is to support the "real world" implementation of effective interventions to manage pain in rural and remote areas. Results from the trials supported by this funding opportunity announcement (FOA) should inform policy makers, payers, community stakeholders, as well as health care providers and patients in the primary care, emergency department, hospital, home health, or dental setting. This FOA requires that the investigators partner with one or more rural healthcare system(s) to plan and implement the intervention. During the planning phase, investigators must develop an additional one or more community-based partnership(s). Studies may propose to integrate multi-component, bundled, or multi-level interventions that have demonstrated efficacy.

Eligibility

Eligible applicants

Government

Federally recognized Native American tribal governments
County governments
State governments
City or township governments
Special district governments
Public and Indian housing authorities

Education

Independent school districts
Public and state institutions of higher education
Private institutions of higher education

Nonprofit

Nonprofits non-higher education with 501(c)(3)
Other Native American tribal organizations
Nonprofits non-higher education without 501(c)(3)

Miscellaneous

Other

Business

For-profit organizations other than small businesses
Small businesses

Additional information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply. Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply. Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Documents

No documents are currently available.

Link to additional information

https://grants.nih.gov/grants/guide/rfa-files/RFA-NR-23-001.html

Archived: December 27, 2022

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$--

Program Funding

Expected awards

$--

Award Minimum

$--

Award Maximum

Funding opportunity number:

RFA-NR-23-001

Cost sharing or matching requirement:

Funding instrument type:

Cooperative agreement

Opportunity Category:

Discretionary

Opportunity Category Explanation:

Category of Funding Activity:

Income security and social services

Education

Health

Category Explanation:

History

Version:

Posted date:

September 16, 2022

Archive date:

December 27, 2022