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NIH Director's Early Independence Award (DP5 Clinical Trial Optional)

Agency: National Institutes of Health

Assistance Listings: 93.310 -- Trans-NIH Research Support

Last Updated: September 3, 2026

Description

The NIH Director's Early Independence Award supports outstanding early-career investigators who are ready to pursue independent research soon after completing their doctoral degree or post-graduate clinical training, without following the traditional postdoctoral path. The award is designed to accelerate the transition to an independent research career. Applications are welcome across all fields relevant to the NIH mission. The Early Independence Award is part of the NIH Common Fund's High-Risk, High-Reward Research Program.

Eligibility

Eligible applicants

Government

  • Federally recognized Native American tribal governments
  • Special district governments
  • County governments
  • City or township governments
  • State governments
  • Public and Indian housing authorities

Nonprofit

  • Nonprofits non-higher education with 501(c)(3)
  • Other Native American tribal organizations
  • Nonprofits non-higher education without 501(c)(3)

Business

  • For-profit organizations other than small businesses
  • Small businesses

Education

  • Independent school districts
  • Private institutions of higher education
  • Public and state institutions of higher education

Miscellaneous

  • Other

Additional information

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Grantor contact information

Description

NIH Director's Early Independence Award Program Please contact via email.

Email

EarlyIndependence@od.nih.gov

EarlyIndependence@od.nih.gov

Documents

No documents are currently available.

Link to additional information

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Forecasted

Estimated Post Date:

March 15, 2027

Estimated Application Due Date:

September 10, 2027

Estimated Due Date Description:

Not available

Estimated Award Date:

August 30, 2028

Estimated Project Start Date:

September 30, 2028

Fiscal Year:

2028

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$5,700,000

Program Funding

10

Expected awards

$350,000

Award Minimum

$350,000

Award Maximum

Funding opportunity number:

RFA-RM-28-004

Cost sharing or matching requirement:

No

Funding instrument type:

Grant

Opportunity Category:

Discretionary

Opportunity Category Explanation:

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Category of Funding Activity:

Health

Category Explanation:

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History

Version:

1

Forecast posted date:

September 3, 2026

Archive date:

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