Translation of Pluripotent Stem Cell Therapies for Blood Diseases (R01)
Agency: National Institutes of Health
Assistance Listings
- 93.839 -- Blood Diseases and Resources Research
Archived opportunityLast Updated: May 13, 2026
View version history on Grants.gov
Description
This FOA issued by the National Heart, Lung, and Blood Institute, National Institutes of Health, encourages Research Project Grant (R01) applications from institutions and organizations that propose collaborative, multidisciplinary, multi-Project Director/Principal Investigator research for the development of new technologies needed to utilize stem cells in future cell therapies to treat sickle cell disease and other blood disorders. This initiative focuses on two key areas that are impediments to further progress: (1) development of techniques to efficiently generate hematopoietic cells by either...
differentiation of human pluripotent stem cells (PSC) or by cellular reprogramming to yield sufficient numbers of GMP quality cells for clinical evaluation; and (2) development of protocols that enable the efficient engraftment of hematopoietic cells derived from pluripotent stem cells or derived by cellular reprogramming. Each multidisciplinary application will designate two or more Project Directors/Principal Investigators. This program will be implemented in collaboration with the ongoing NHLBI Progenitor Cell Biology Consortium (http://www.progenitorcells.org/) and will add separate additional research projects. Extensive collaboration is expected between the existing Consortium Hubs, and the new group(s) are also expected to collaborate extensively with the Consortium Hubs.
Eligibility
Eligible applicants
Business
- For-profit organizations other than small businesses
- Small businesses
Government
- Public and Indian housing authorities
- County governments
- City or township governments
- State governments
- Special district governments
- Federally recognized Native American tribal governments
Miscellaneous
- Other
Education
- Public and state institutions of higher education
- Private institutions of higher education
- Independent school districts
Nonprofit
- Other Native American tribal organizations
- Nonprofits non-higher education with 501(c)(3)
- Nonprofits non-higher education without 501(c)(3)
Additional information
Other Eligible Applicants include the following:
Alaska Native and Native Hawaiian Serving Institutions; Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession; Foreign (non-U.S.) components of U.S. Organizations are not allowed.
Grantor contact information
Description
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Documents
No documents are currently available.
Link to additional information
Archived: February 7, 2014
Award
$--
Program Funding
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Expected awards
$--
Award Minimum
$--
Award Maximum
Funding opportunity number:
PA-11-186
Cost sharing or matching requirement:
No
Funding instrument type:
Grant
Opportunity Category:
Discretionary
Opportunity Category Explanation:
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Category of Funding Activity:
Health
Category Explanation:
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History
Version:
2
Posted date:
March 28, 2011
Archive date:
February 7, 2014
