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Single Source Competition for Continuation of Understanding and Targeting the Pathophysiology of Youth-Onset Type 2 Diabetes Clinical Centers (U01 Clinical Trial Not Allowed)

Agency: National Institutes of Health

Assistance Listings: 93.847 -- Diabetes, Digestive, and Kidney Diseases Extramural Research

Last Updated: August 4, 2026

Description

The DISCOVERY of Risk Factors for Type 2 Diabetes in Youth Study is a multi-center longitudinal consortium conducted across 19 clinical sites to identify risk factors and biological mechanisms driving progression to youth-onset type 2 diabetes. The study is actively recruiting and following early pubertal youth at high risk for the disease with longitudinal follow-up currently underway. The current Biostatistics Research Center (BRC) serves as the consortium's central coordinating center, managing protocol implementation, data management, quality assurance, statistical design and analysis, and inter-site and consortium-wide coordination.  The BRC has established the robust infrastructure and standardized processes required to support the study and preserve the integrity of the longitudinal dataset. 

The purpose of this single-source solicitation is to support completion of the scientific objectives of the ongoing DISCOVERY clinical consortium.

Eligibility

Eligible applicants

Miscellaneous

  • Other

Additional information

This is a Single Source competition that will invite application(s) from eligible organization(s) to apply. Please see Eligibility Section for additional information. In accordance with NIH standard peer-review processes, the application(s) will be peer-reviewed, and only meritorious application(s) will be considered for funding.

Grantor contact information

Description

Division of Diabetes, Endocrinology and Metabolic Diseases NIDDK_DEM@nih.gov

Email

Division of Diabetes, Endocrinology and Metabolic Diseases

NIDDK_DEM@nih.gov

Documents

No documents are currently available.

Link to additional information

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Forecasted

Estimated Post Date:

February 2, 2027

Estimated Application Due Date:

March 10, 2027

Estimated Due Date Description:

Not available

Estimated Award Date:

November 1, 2027

Estimated Project Start Date:

December 1, 2027

Fiscal Year:

2028

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$35,000,000

Program Funding

1

Expected awards

$--

Award Minimum

$--

Award Maximum

Funding opportunity number:

RFA-DK-28-115

Cost sharing or matching requirement:

No

Funding instrument type:

Cooperative agreement

Opportunity Category:

Discretionary

Opportunity Category Explanation:

--

Category of Funding Activity:

Health

Category Explanation:

--

History

Version:

1

Forecast posted date:

August 4, 2026

Archive date:

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