The purpose of this notice of funding opportunity (NOFO) is to support coordinated, multidisciplinary research on structure-based immunogen design aimed at preventing and controlling HIV. The goal is to develop HIV immunogens and treatment strategies that use or stimulate broadly neutralizing antibodies (bNAbs), and to advance these approaches toward clinical testing for both prevention and therapy. Technologies and methods developed through this initiative are expected to have broad applications in other fields that face similar challenges in targeting antigens for therapeutics and vaccine development. 

Government

• County governments
• Federally recognized Native American tribal governments
• Public and Indian housing authorities
• Special district governments
• City or township governments
• State governments

Education

• Private institutions of higher education
• Public and state institutions of higher education
• Independent school districts

Business

• For-profit organizations other than small businesses
• Small businesses

Nonprofit

• Other Native American tribal organizations
• Nonprofits non-higher education with 501(c)(3)
• Nonprofits non-higher education without 501(c)(3)

Miscellaneous

• Other