Advanced Development and Validation of Emerging Biospecimen Science Technologies for Basic and Clinical Cancer Research (R33 Clinical Trial Not Allowed)
Agency: National Institutes of Health
Assistance Listings: 93.394 -- Cancer Detection and Diagnosis Research
Description
Through this Notice of Funding Opportunity (NOFO), National Cancer Institute (NCI) solicits grant applications proposing exploratory research projects focused on further development and validation of emerging technologies that improve the quality and handling of samples used for cancer research or clinical care. Through this NOFO, NCI will support the development of tools, devices, assays, and associated methods for the collection, handling, processing, preservation, or storage of cancer-relevant biospecimens and their derivatives. This includes tools with new capabilities to preserve or protect sample integrity, or establish verification criteria for quality assessment/quality control and address issues related to pre-analytical degradation of of targeted analytes. Major feasibility gaps for the technology or methodology should have already been overcome, as demonstrated by supportive preliminary data, but the tool requires further development and rigorous validation. These technologies are expected to accelerate and/or enhance research in cancer biology, early detection and screening, clinical diagnosis, treatment, or epidemiology and/or address issues associated with cancer health disparities.This funding opportunity is part of a broader NCI-sponsored Innovative Molecular Analysis Technologies (IMAT) Program.
Eligibility
Eligible applicants
Education
- Independent school districts
- Public and state institutions of higher education
- Private institutions of higher education
Nonprofit
- Nonprofits non-higher education with 501(c)(3)
- Other Native American tribal organizations
- Nonprofits non-higher education without 501(c)(3)
Government
- County governments
- State governments
- Federally recognized Native American tribal governments
- Public and Indian housing authorities
- City or township governments
- Special district governments
Business
- For-profit organizations other than small businesses
- Small businesses
Miscellaneous
- Other
Additional information
Grantor contact information
Description
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
Documents
| File name | Description | Last updated |
|---|---|---|
| RFA-CA-25-004-Full-Announcement.html | RFA-CA-25-004 Full Announcement Text | Dec 16, 2024 04:35 PM UTC |
Link to additional information
https://grants.nih.gov/grants/guide/rfa-files/RFA-CA-25-004.html
Archived: February 7, 2026
Award
$300,000
Program Funding
2
Expected awards
$--
Award Minimum
$300,000
Award Maximum
Funding opportunity number:
RFA-CA-25-004
Cost sharing or matching requirement:
Funding instrument type:
Grant
Opportunity Category:
Discretionary
Opportunity Category Explanation:
Category of Funding Activity:
Education
Health
Category Explanation:
History
Version:
2
Posted date:
December 16, 2024
Archive date:
February 7, 2026
