Opportunity Listing - Targeting Cell Surface HIV Envelope for Cell Elimination (R01 Clinical Trial Not Allowed)

Targeting Cell Surface HIV Envelope for Cell Elimination (R01 Clinical Trial Not Allowed)

Agency: National Institutes of Health

Assistance Listings: 93.855 -- Allergy and Infectious Diseases Research

Last Updated: February 19, 2026

Description

The purpose of this notice of funding opportunity (NOFO) is to support the investigation of HIV-1 Envelope (Env) cell surface expression, the structural mechanism of biologic-mediated cell killing, and the development of novel approaches to enhance the recognition and elimination of Env-expressing, HIV-1 infected cells. These studies are expected to inform the development of immunotherapies and targeted vaccines for HIV-1 prevention and cure.

Eligibility

Eligible applicants

Education

Public and state institutions of higher education
Independent school districts
Private institutions of higher education

Nonprofit

Nonprofits non-higher education with 501(c)(3)
Other Native American tribal organizations
Nonprofits non-higher education without 501(c)(3)

Government

City or township governments
County governments
Special district governments
State governments
Federally recognized Native American tribal governments
Public and Indian housing authorities

Business

Small businesses
For-profit organizations other than small businesses

Miscellaneous

Other

Additional information

Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.

Grantor contact information

Description

NIH Grants Information grantsinfo@nih.gov

Email

See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.

grantsinfo@nih.gov

Documents

File name	Description	Last updated
PAR-25-300-Full-Announcement.html	PAR-25-300 Full Announcement Text	Dec 2, 2024 08:22 PM UTC

Link to additional information

https://grants.nih.gov/grants/guide/pa-files/PAR-25-300.html

Archived: March 21, 2026

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$--

Program Funding

Expected awards

$--

Award Minimum

$--

Award Maximum

Funding opportunity number:

PAR-25-300

Cost sharing or matching requirement:

Funding instrument type:

Grant

Opportunity Category:

Discretionary

Opportunity Category Explanation:

Category of Funding Activity:

Health

Category Explanation:

History

Version:

Posted date:

December 2, 2024

Archive date:

March 21, 2026