ADVANCING TOXICOKINETICS FOR EFFICIENT AND ROBUST CHEMICAL EVALUATIONS
Agency: Environmental Protection Agency
Assistance Listings
- 66.509 -- Science To Achieve Results (STAR) Research Program
Archived opportunityLast Updated: May 13, 2026
Important dates
- Archived: October 24, 2019
- Closed: September 24, 2019
See Section IV of the solicitation for close date information.
Award details
- Expected project funding: $4,000,000
- Expected awards: 5
Award min.
Not specified
Award max.
$800,000
- Funding opportunity number:EPA-G2019-STAR-D1
- Cost sharing or matching requirement:No
- Funding instrument type:
- Grant
- Opportunity Category:Discretionary
- Opportunity Category Explanation:Not specified
- Category of Funding Activity:
- Environment
- Category Explanation:Not specified
History
- Posted date: July 25, 2019
- Archive date: October 24, 2019
- Version: 2
Summary
Jump to documentsThe U.S. Environmental Protection Agency (EPA), as part of its Science to Achieve Results (STAR) program, is seeking applications proposing to advance the development of chemical toxicokinetic tools and approaches for broader applicability during chemical evaluations, with an emphasis on their application within new approach methodology (NAM) frameworks. Toxicokinetics describes the absorption, distribution, metabolism, and excretion of chemicals and their metabolites by the body, and as such provides a framework for extrapolating in vivo doses of concern from in vitro-derived concentrations that cause perturbations at the cellular or molecular level. The incorporation of new methods, tools and approaches can simultaneously improve predictivity, reduce uncertainty and build confidence in the successful application of such extrapolations.
Eligibility
Miscellaneous
- Other
Additional information on eligibility
See Section III of the solicitation for eligibility information.
Documents
| File name | Description | Last updated |
|---|---|---|
| httk_rfa_061719_ioaa_edits_ncer_ddd_data_highlight_mrh_5_1.pdf | announcement | Aug 16, 2019 02:23 PM UTC |
Agency contact information
Email: jones.debram@epa.gov
jones.debram@epa.gov
Technical Contact: Barbara Klieforth; phone: 202-564-7223; email: klieforth.barbara@epa.gov
Eligibility Contact: Ron Josephson; phone: 202-564-7823; email: josephson.ron@epa.gov
Electronic Submissions Contact: Debra M. Jones; phone: 202-564-7839; email: jones.debram@epa.gov
