NIH Research Project Grant (Parent R01 Basic Experimental Studies with Humans Required)
Agency: National Institutes of Health
- 93.121 -- Oral Diseases and Disorders Research
- 93.113 -- Environmental Health
- 93.233 -- National Center on Sleep Disorders Research
- 93.865 -- Child Health and Human Development Extramural Research
- 93.866 -- Aging Research
- 93.273 -- Alcohol Research Programs
- 93.839 -- Blood Diseases and Resources Research
- 93.853 -- Extramural Research Programs in the Neurosciences and Neurological Disorders
- 93.838 -- Lung Diseases Research
- 93.279 -- Drug Use and Addiction Research Programs
- 93.840 -- Translation and Implementation Science Research for Heart, Lung, Blood Diseases, and Sleep Disorders
- 93.307 -- Minority Health and Health Disparities Research
- 93.847 -- Diabetes, Digestive, and Kidney Diseases Extramural Research
- 93.213 -- Research and Training in Complementary and Integrative Health
- 93.867 -- Vision Research
- 93.837 -- Cardiovascular Diseases Research
- 93.361 -- Nursing Research
- 93.173 -- Research Related to Deafness and Communication Disorders
- 93.242 -- Mental Health Research Grants
- 93.399 -- Cancer Control
Archived opportunityLast Updated: May 13, 2026
View version history on Grants.gov
Description
The NIH Research Project Grant supports a discrete, specified, circumscribed project in areas representing the specific interests and competencies of the investigator(s).This Parent Notice of Funding Opportunity is for basic science experimental studies involving humans, referred to in NOT-OD-18-212 as prospective basic science studies involving human participants. These studies fall within the NIH definition of a clinical trial and also meet the definition of basic research. Types of studies that should submit under this NOFO include studies that prospectively assign human participants to conditions (i.e., experimentally manipulate independent variables) and that assess biomedical or behavioral outcomes in humans for the purpose of understanding the fundamental aspects of phenomena without specific application towards processes or products in mind. Studies conducted with specific applications toward processes or products in mind should submit under the appropriate Clinical Trials Required or Clinical Trial Optional NOFO.The proposed project must be related to the programmatic interests of one or more of the participating NIH Institutes and Centers (ICs) based on their scientific missions.
Eligibility
Eligible applicants
Education
- Private institutions of higher education
- Public and state institutions of higher education
- Independent school districts
Business
- For-profit organizations other than small businesses
- Small businesses
Government
- Public and Indian housing authorities
- County governments
- State governments
- Special district governments
- City or township governments
- Federally recognized Native American tribal governments
Nonprofit
- Nonprofits non-higher education without 501(c)(3)
- Other Native American tribal organizations
- Nonprofits non-higher education with 501(c)(3)
Miscellaneous
- Other
Additional information
Grantor contact information
Description
See Section VII. Agency Contacts within the full opportunity announcement for all other inquires.
Documents
| File name | Description | Last updated |
|---|---|---|
| PA-25-303-Full-Announcement.html | PA-25-303 Full Announcement Text | Dec 18, 2024 05:52 PM UTC |
Link to additional information
Archived: June 23, 2026
Award
$--
Program Funding
--
Expected awards
$--
Award Minimum
$--
Award Maximum
Funding opportunity number:
PA-25-303
Cost sharing or matching requirement:
Funding instrument type:
Grant
Opportunity Category:
Discretionary
Opportunity Category Explanation:
Category of Funding Activity:
Education
Environment
Food and nutrition
Health
Income security and social services
Category Explanation:
History
Version:
2
Posted date:
December 18, 2024
Archive date:
June 23, 2026
