Advancing Translational and Clinical Probiotic/Prebiotic and Human Microbiome Research (R01 Clinical Trial Optional)
Agency: National Institutes of Health
Assistance Listings
- 93.213 -- Research and Training in Complementary and Integrative Health
- 93.393 -- Cancer Cause and Prevention Research
- 93.321 -- Dietary Supplement Research Program
Archived opportunityLast Updated: May 13, 2026
View version history on Grants.gov
Description
The purpose of this funding opportunity announcement (FOA) is twofold: 1. to accelerate translational and clinical Phase I and II a/b safety and efficacy studies for substantiating measurable functional benefits of probiotic/prebiotic components and/or their combinations; and; 2. to understand the underlying mechanisms of their action(s), and variability in responses to these interventions. This FOA calls for interdisciplinary collaborations across scientific disciplines engaged in microbiome and pro/prebiotic research including, but not limited to: nutritional science, microbiology, virology, microecology...
and microbiome, genomics, immunology, computational biology, chemistry, bioengineering, as well as integration of omics and computational approaches in DNA technologies. This FOA will not support phase III clinical trials.
Eligibility
Eligible applicants
Government
- County governments
- Federally recognized Native American tribal governments
- Special district governments
- Public and Indian housing authorities
- City or township governments
- State governments
Education
- Independent school districts
- Private institutions of higher education
- Public and state institutions of higher education
Miscellaneous
- Other
Business
- Small businesses
- For-profit organizations other than small businesses
Nonprofit
- Other Native American tribal organizations
- Nonprofits non-higher education with 501(c)(3)
- Nonprofits non-higher education without 501(c)(3)
Additional information
Other Eligible Applicants include the following: Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISISs); Eligible Agencies of the Federal Government; Faith-based or Community-based Organizations; Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Indian/Native American Tribal Governments (Other than Federally Recognized); Non-domestic (non-U.S.) Entities (Foreign Organizations); Regional Organizations; Tribally Controlled Colleges and Universities (TCCUs) ; U.S. Territory or Possession.
Grantor contact information
Description
NIH OER Webmaster
FBOWebmaster@OD.NIH.GOV
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Documents
No documents are currently available.
Link to additional information
Archived: October 13, 2021
Award
$--
Program Funding
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Expected awards
$--
Award Minimum
$--
Award Maximum
Funding opportunity number:
PA-18-902
Cost sharing or matching requirement:
No
Funding instrument type:
Grant
Opportunity Category:
Discretionary
Opportunity Category Explanation:
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Category of Funding Activity:
Health
Education
Category Explanation:
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History
Version:
1
Posted date:
August 14, 2018
Archive date:
October 13, 2021
