Skip to main content

NIDA Avenir Program: Fundamental Mechanistic Research in Addiction Science

Agency: National Institutes of Health

Assistance Listings: 93.279 -- Drug Use and Addiction Research Programs

Last Updated: September 10, 2026

Description

Avenir, the French word for "future," reflects NIDA's commitment to developing the next generation of leaders in addiction science. Since 2015, the Avenir Program has supported exceptionally creative early stage investigators (ESIs) in launching innovative research programs. NIDA is now expanding this program to support bold mechanistic research across a broader range of addiction science, including genetic, epigenetic, molecular, cellular, circuit, chemical, pharmacological, behavioral, and cognitive processes relevant to Substance Use Disorders (SUDs).

This initiative is intended to catalyze high-risk, high-reward research and attract outstanding new investigators, including those from outside the addiction field. Applications proposing novel, unconventional, or interdisciplinary wet-lab and/or data science approaches to advance understanding of the mechanisms underlying SUDs are encouraged. The Avenir Program is designed for ESIs who may lack the preliminary data needed for an R01 application but propose high-impact research and show strong potential to become future leaders in fundamental mechanistic addiction science.

Grant authorities that allow NIDA to forecast this opportunity are 42 U.S.C. §§ 241 and 284.

Eligibility

Eligible applicants

Education

  • Public and state institutions of higher education
  • Independent school districts
  • Private institutions of higher education

Nonprofit

  • Nonprofits non-higher education without 501(c)(3)
  • Nonprofits non-higher education with 501(c)(3)
  • Other Native American tribal organizations

Government

  • City or township governments
  • Federally recognized Native American tribal governments
  • County governments
  • Special district governments
  • Public and Indian housing authorities
  • State governments

Business

  • Small businesses
  • For-profit organizations other than small businesses

Miscellaneous

  • Other

Additional information

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;

Grantor contact information

Description

National Institute on Drug Abuse (NIDA Please contact via e-mail.

Email

Inbox for NIDA Genetics, Epigenetics, Development Branch Program Staff

NIDA_GED_Program@nida.nih.gov

Documents

No documents are currently available.

Link to additional information

--

Forecasted

Estimated Post Date:

February 1, 2027

Estimated Application Due Date:

May 26, 2027

Estimated Due Date Description:

Not available

Estimated Award Date:

April 1, 2028

Estimated Project Start Date:

April 1, 2028

Fiscal Year:

2028

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$3,000,000

Program Funding

5

Expected awards

$--

Award Minimum

$375,000

Award Maximum

Funding opportunity number:

RFA-DA-28-002

Cost sharing or matching requirement:

No

Funding instrument type:

Grant

Opportunity Category:

Discretionary

Opportunity Category Explanation:

--

Category of Funding Activity:

Health

Category Explanation:

--

History

Version:

1

Forecast posted date:

September 10, 2026

Archive date:

--

HHS.gov

An official website of the U.S. Department of Health and Human Services

Looking for U.S. government information and services? Visit USA.gov