The purpose of this notice of funding opportunity (NOFO) is to solicit applications for an Autoimmune Diseases Statistical and Clinical Coordinating Center (AD-SCCC). The AD-SCCC will provide clinical study and clinical trial development, management, repository management, manuscript production, study archiving and biostatistical support for ongoing and future clinical trials in the areas of autoimmune diseases, mucosal immunology, and inborn errors of immunity while maintaining and supporting all relevant regulatory requirements. The AD-SCCC may also collaborate with and assist the National Institute of Allergy and Infectious Diseases (NIAID) Clinical Site Monitoring Center (CSMC), and other NIAID resources.