Opportunity Listing - Limited Competition: Chronic Kidney Diseases of UnceRtain Etiology (CKDu) in Agricultural Communities (CURE) Research Consortium- Field Epidemiology Sites

Limited Competition: Chronic Kidney Diseases of UnceRtain Etiology (CKDu) in Agricultural Communities (CURE) Research Consortium- Field Epidemiology Sites

Agency: National Institutes of Health

Assistance Listings: 93.847 -- Diabetes, Digestive, and Kidney Diseases Extramural Research

Last Updated: September 30, 2025

Description

The purpose of this funding opportunity is to advance the NIH mission by supporting the continuation of the Consortium to Study Chronic Kidney Disease of UnceRtain Etiology (CKDu) in Agricultural Communities (CURE).

Chronic Kidney Disease of Uncertain Etiology (CKDu) causes kidney failure in rural areas of many Low and Middle Income Countries, resulting in a large death toll among the young working age population. Environmental factors are suspected to be causative, but family and geographic clustering add consideration of unrecognized genetic susceptibility. The risk factors identified in other countries are encountered by U.S. patients, so this research will offer valuable insights into the development and progression of tubulointerstitial renal diseases, with broad implications for understanding kidney health and disease in the U.S.

style="margin-left:0in;">NIDDK, NIEHS, and FIC have jointly funded a consortium that includes Field Epidemiology Sites, a Renal and Environmental Science Core, and a Data Coordinating Center to find causes and potential interventions for CKDu since 2021. This NOFO requests renewal applications for the Field Epidemiology Sites that will continue to identify, recruit, and retain participants in CKDu endemic areas, conduct study visits, and collect biological and environmental samples. Consortium members will continue to collaborate to maximize scientific opportunities and enable discovery science to understand the etiologies of CKDu, the exposures that initiate and affect progression of tubulointerstitial kidney disease, potential therapeutic targets, and future opportunities for public health interventions. The CURE Consortium will serve as a resource for ancillary studies.

This is a forecast for a limited competition Notice of Funding Opportunity (NOFO) that will invite application(s) from eligible organizations to apply. Application(s) will be peer-reviewed and only funded if meritorious.

Eligibility

Eligible applicants

Government

Federally recognized Native American tribal governments
County governments
State governments
Public and Indian housing authorities

Education

Private institutions of higher education
Public and state institutions of higher education

Business

Small businesses
For-profit organizations other than small businesses

Miscellaneous

Other

Nonprofit

Other Native American tribal organizations

Additional information

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Grantor contact information

Description

Email

susan.mendley@nih.gov

Documents

No documents are currently available.

Link to additional information

Forecasted

Estimated Post Date:

April 1, 2026

Estimated Application Due Date:

July 1, 2026

Estimated Due Date Description:

Not available

Estimated Award Date:

January 1, 2027

Estimated Project Start Date:

February 1, 2027

Fiscal Year:

2027

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$6,000,000

Program Funding

Expected awards

$--

Award Minimum

$--

Award Maximum

Funding opportunity number:

RFA-DK-27-130

Cost sharing or matching requirement:

Funding instrument type:

Cooperative agreement

Opportunity Category:

Discretionary

Opportunity Category Explanation:

Category of Funding Activity:

Health

Category Explanation:

History

Version:

Forecast posted date:

September 30, 2025

Archive date: