(R&D) and associated infrastructure support activities to develop innovative technologies that offer the promise of dramatically improved performance for its mission needs as stated above, while maximizing the impact of NE resources. NE strives to promote integrated and collaborative research conducted by national laboratory, university, industry, and international partners under the direction of NE’s programs; deploy innovative nuclear energy technologies to the market; and optimize the benefits of nuclear energy. All applications submitted under this CINR Phase II Continuation NOFO must demonstrate a strong tie to at least one of these four mission priorities and highlight how they support DOE priorities. • NE is seeking CINR Phase II Continuation applications from U.S. universities to conduct nuclear energy-related research to help meet the objectives of the major NE funded research areas. • The NOFO is focused on continuing promising research pathways by soliciting applications that directly complement and extend research that has previously been awarded research through NEUP. • CINR awarded projects, including R&D and IRPs, that conclude between January 1, 2026, and September 30, 2026, are eligible to apply. Nuclear Science User Facilities (NSUF) Access Only projects are NOT eligible to apply to this funding opportunity. Instead, they should apply to the NSUF Access Only process under the separate FY 2026 CINR NOFO for additional access to NSUF capabilities.