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HEAL: Translating Addiction Epidemiology, Prevention, Treatment, and Recovery Research into Practice (R61/R33 - Clinical Trial Optional)

Agency: National Institutes of Health

Assistance Listings: 93.279 -- Drug Use and Addiction Research Programs

Last Updated: December 9, 2025

Description

The National Institute on Drug Abuse (NIDA), with other NIH Institutes, intends to publish a Notice of Funding Opportunity (NOFO) to solicit applications to support action-oriented research that accelerates the translation of addiction epidemiology, prevention, treatment, and recovery research to practice addressing both the opioid crisis and overdose events. Research supported under this initiative would focus on identifying and characterizing malleable factors and addressing barriers or facilitators to reducing substance use, misuse and overdose deaths at the individual, provider, organizational, community, or system levels. The emphasis would be on exploring and developing effective, replicable, and scalable approaches for accelerating the movement of evidence-based and promising treatments and preventive interventions into routine use. Specific priority areas would include, but not be limited to: recovery, prevention, pain/addiction intersections, engaging family and loved ones, transitions across care settings (e.g., inpatient treatment to community treatment), mental health integration, improving quality and efficiency of existing services and interventions,  examining substance use and health  outcomes and meaningful real-time data capture and use to improve services and public health approaches to reducing substance use, misuse, addiction, and overdose. Applications are not being solicited at this time. Notice is being provided to allow potential applicants sufficient time to develop meaningful collaborations and responsive projects. This NOFO will utilize the R61/R33 activity code. Investigators with expertise and insights into this area of addiction epidemiology, prevention, treatment, recovery and health services research are encouraged to begin to consider applying for this new NOFO. In addition, collaborative investigations combining expertise in modeling, health economics, implementation science, translation, or engagement science will be encouraged, and these investigators should also begin considering applying for this application.

Eligibility

Eligible applicants

Education

  • Private institutions of higher education
  • Public and state institutions of higher education
  • Independent school districts

Nonprofit

  • Nonprofits non-higher education with 501(c)(3)
  • Other Native American tribal organizations

Business

  • For-profit organizations other than small businesses
  • Small businesses

Government

  • State governments
  • Public and Indian housing authorities
  • County governments
  • Federally recognized Native American tribal governments

Additional information

Grantor contact information

Description

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Email

tisha.wiley@nih.gov

tisha.wiley@nih.gov

Documents

No documents are currently available.

Link to additional information

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Forecasted

Estimated Post Date:

April 9, 2026

Estimated Application Due Date:

June 9, 2026

Estimated Due Date Description:

Not available

Estimated Award Date:

April 1, 2027

Estimated Project Start Date:

April 1, 2027

Fiscal Year:

2027

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$--

Program Funding

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Expected awards

$--

Award Minimum

$--

Award Maximum

Funding opportunity number:

FOR-DA-26-001

Cost sharing or matching requirement:

No

Funding instrument type:

Grant

Opportunity Category:

Discretionary

Opportunity Category Explanation:

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Category of Funding Activity:

Health

Category Explanation:

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History

Version:

3

Forecast posted date:

May 5, 2025

Archive date:

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