This initiative will support research on the development, validation, feasibility, and effectiveness of innovative digital health interventions or tools (including mobile health) specifically suited for underserved settings in the U.S. and globally. Research should utilize new or emerging technologies, platforms, systems, and/or analytics to address high priority health problems, expand the evidence base for the use of digital health technology to improve clinical and public health outcomes, and strengthen research collaborations between U.S. and low- and middle-income country (LMIC) researchers. Applications must include reciprocal innovation methodologies – bidirectional and iterative exchange of ideas, resources, and innovation approaches to address shared health challenges in the U.S. and a LMIC.  Through this utilization of unique data, environments, and populations in domestic and international contexts, awards will maximize generalizable knowledge produced and optimize potential benefit to U.S. and LMIC populations.  

Government

• Federally recognized Native American tribal governments
• County governments
• Special district governments
• Public and Indian housing authorities
• State governments
• City or township governments

Business

• For-profit organizations other than small businesses
• Small businesses

Nonprofit

• Other Native American tribal organizations
• Nonprofits non-higher education without 501(c)(3)
• Nonprofits non-higher education with 501(c)(3)

Education

• Independent school districts
• Public and state institutions of higher education
• Private institutions of higher education

Miscellaneous

• Other