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Continuing Enhanced National Surveillance for Prion Diseases in the United States

Agency: Centers for Disease Control - NCEZID

Assistance Listings: 93.317 -- Emerging Infections Programs

Last Updated: July 10, 2026

Description

The CDC announces the availability of FY 2027 funds for a cooperative agreement to continue enhanced national surveillance for human prion diseases, also known as transmissible spongiform encephalopathies (TSEs), in the United States. The purpose is to continue an active surveillance program to help confirm suspected and clinically diagnosed cases of human prion disease and to monitor the occurrence of potentially emerging human prion diseases in the United States. Outcomes are enhanced national surveillance for always fatal human prion diseases through improved diagnoses and continued monitoring for emerging or new prion diseases in the United States. These outcomes are accomplished through the funding of a specialized center to conduct state-of-the-art diagnostic techniques. Prion diseases can only be confirmed through brain tissue analyses, and many facilities lack the expertise and/or the willingness, due to infection control concerns, to handle and accurately diagnose specimens from suspected cases. Since 1997, the Centers for Disease Control and Prevention (CDC) has funded a center to provide prion disease diagnostic services, which has allowed for disease confirmation, evaluation of disease trends over time, and identification of disease subtypes. Data have been shared with CDC experts who partner with center staff, providing guidance and epidemiological knowledge. This collaboration has contributed to accurate national surveillance findings and helped to provide confidence that novel prion diseases, such as a human form of the animal prion disease, chronic wasting disease, have not been occurring in the country.

Eligibility

Eligible applicants

Business

  • Small businesses
  • For-profit organizations other than small businesses

Nonprofit

  • Other Native American tribal organizations
  • Nonprofits non-higher education without 501(c)(3)
  • Nonprofits non-higher education with 501(c)(3)

Government

  • State governments
  • County governments
  • Federally recognized Native American tribal governments
  • City or township governments
  • Special district governments

Education

  • Independent school districts
  • Public and state institutions of higher education
  • Private institutions of higher education

Miscellaneous

  • Unrestricted

Additional information

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Grantor contact information

Description

Lisa Angel 404-639-1083

Email

langel@cdc.gov

langel@cdc.gov

Documents

No documents are currently available.

Link to additional information

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Forecasted

Estimated Post Date:

December 29, 2026

Estimated Application Due Date:

March 27, 2027

Estimated Due Date Description:

Not available

Estimated Award Date:

August 31, 2027

Estimated Project Start Date:

August 31, 2027

Fiscal Year:

2027

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$25,000,000

Program Funding

1

Expected awards

$3,000,000

Award Minimum

$25,000,000

Award Maximum

Funding opportunity number:

CDC-RFA-CK-27-0046

Cost sharing or matching requirement:

No

Funding instrument type:

Cooperative agreement

Opportunity Category:

Discretionary

Opportunity Category Explanation:

--

Category of Funding Activity:

Health

Category Explanation:

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History

Version:

1

Forecast posted date:

July 10, 2026

Archive date:

April 26, 2027

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