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INCLUDE Project: Omics Phenotypes Related to Down Syndrome (X01 Clinical Trial Not Allowed)

Agency: National Institutes of Health

Assistance Listings: 93.T21 -- INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE

Last Updated: July 28, 2026

Description

The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. The purpose of this Notice of Funding Opportunity (NOFO) is to solicit applications to submit samples to NIH INCLUDE Project-supported resources to generate a large volume of integrated genomic and multi-omics data that will facilitate discovery of the molecular mechanisms of health conditions related to Down syndrome. The resulting data, and associated clinical and phenotypic data, will become part of the INCLUDE Data Hub for sharing with the research community. No funding will be provided directly to applicants under this NOFO. Applicants are encouraged to propose omics assays of existing biospecimens collected from individuals with Down syndrome and controls. 

Eligibility

Eligible applicants

Education

  • Public and state institutions of higher education
  • Independent school districts
  • Private institutions of higher education

Government

  • County governments
  • Federally recognized Native American tribal governments
  • State governments
  • Public and Indian housing authorities
  • Special district governments
  • City or township governments

Nonprofit

  • Other Native American tribal organizations
  • Nonprofits non-higher education with 501(c)(3)
  • Nonprofits non-higher education without 501(c)(3)

Miscellaneous

  • Other

Business

  • Small businesses
  • For-profit organizations other than small businesses

Additional information

Other Eligible ApplicantsIndian/Native American Tribal Governments (Other than Federally Recognized);Eligible Agencies of the Federal Government;U.S. Territory or Possession;Faith-based or Community-based Organizations;Regional Organizations;Non-domestic (non-U.S.) Entities (Foreign Institutions).

Grantor contact information

Description

The INCLUDE Project Please contact via e-mail.

Email

DownSyndromeINCLUDE@mail.nih.gov

DownSyndromeINCLUDE@mail.nih.gov

Documents

No documents are currently available.

Link to additional information

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Forecasted

Estimated Post Date:

April 15, 2027

Estimated Application Due Date:

June 15, 2027

Estimated Due Date Description:

Not available

Estimated Award Date:

April 1, 2028

Estimated Project Start Date:

April 1, 2028

Fiscal Year:

2027

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$--

Program Funding

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Expected awards

$--

Award Minimum

$--

Award Maximum

Funding opportunity number:

PAR-27-117

Cost sharing or matching requirement:

No

Funding instrument type:

Grant

Opportunity Category:

Discretionary

Opportunity Category Explanation:

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Category of Funding Activity:

Health

Category Explanation:

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History

Version:

1

Forecast posted date:

July 28, 2026

Archive date:

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