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GREGoRi Technology Integration Center (U01, Clinical Trials Optional)

Agency: National Institutes of Health

Assistance Listings: 93.172 -- Human Genome Research

Last Updated: June 18, 2026
The Genomics Research to Elucidate the Genetics of Rare Diseases:innovation (GREGoRi) initiative seeks to accelerate a paradigm shift in rare disease diagnosis by reimagining the tools, molecular technologies and analytical approaches used to identify the causal gene(s) and/or variant(s) underlying rare genetic disorders. The purpose of this Notice of Funding Opportunity is to establish the GREGoRi Technology Integration Center, which will enable the development of standards and best practices for applying new and emerging molecular methods in rare disease diagnosis. A major deliverable of the Center...

Eligibility

Eligible applicants

Government

  • County governments
  • Public and Indian housing authorities
  • City or township governments
  • Special district governments
  • Federally recognized Native American tribal governments
  • State governments

Nonprofit

  • Other Native American tribal organizations
  • Nonprofits non-higher education with 501(c)(3)
  • Nonprofits non-higher education without 501(c)(3)

Business

  • For-profit organizations other than small businesses
  • Small businesses

Education

  • Independent school districts
  • Public and state institutions of higher education
  • Private institutions of higher education

Miscellaneous

  • Other

Additional information

Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International Collaborations:Non-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Grantor contact information

Description

GREGoRi Program Team nhgri-gregor@mail.nih.gov

Email

nhgri-gregor@mail.nih.gov

nhgri-gregor@mail.nih.gov

Documents

File nameDescriptionLast updated
RFA-HG-27-012-Full-Announcement.html
RFA-HG-27-012-Full-Announcement.html
Jun 18, 2026 05:46 PM UTC

Link to additional information

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Closing: October 30, 2026

Application process

This site is a work in progress. Go to www.grants.gov to apply, track application status, and subscribe to updates.

Award

$3,000,000

Program Funding

1

Expected awards

$--

Award Minimum

$2,250,000

Award Maximum

Funding opportunity number:

RFA-HG-27-012

Cost sharing or matching requirement:

No

Funding instrument type:

Cooperative agreement

Opportunity Category:

Discretionary

Opportunity Category Explanation:

--

Category of Funding Activity:

Health

Category Explanation:

--

History

Version:

1

Posted date:

June 18, 2026

Archive date:

December 29, 2026

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